[Endoribonuclease Dicer, encoded by the human DICER1 gene, possesses an RNA helicase motif, containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. It is required by the RNA interference in cleaving double-stranded RNA as well as small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. The 21 to 23 bp double-stranded RNAs (siRNAs) generated target the selective destruction of homologous RNAs. (From OMIM, Swiss-Port, and NCI) ( NCI )]
UMLS (NCI) C1309483Dicer
DICER1
DICER1 Protein
EC 3.1.26.-
Endoribonuclease Dicer
Helicase with RNase Motif
Helicase-MOI
HERNA
Homolog of Drosophila Dicer
K12H4.8-Like
KIAA0928
- Amino Acid, Peptide, or Protein
- Enzyme