DHPG sodium
[The sodium salt form of ganciclovir, a synthetic, antiviral, purine nucleoside analog with antiviral activity, especially against cytomegalovirus (CMV). Ganciclovir sodium is a prodrug that is phosphorylated and subsequently converted into its triphosphate form, the active metabolite ganciclovir-5-triphosphate (ganciclovir-TP), in the infected cells by cellular kinases. Ganciclovir-TP competes as a substrate with nucleotide triphosphates for viral DNA polymerase. Once it gets incorporated into DNA strand, it prevents further polymerization of DNA, thereby interfering with viral DNA replication. ( NCI )]
UMLS (NCI) C0282399- Nucleic Acid, Nucleoside, or Nucleotide
- Pharmacologic Substance
Relation/PAR: 2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one
Relation/CHD: GANCICLOVIR (AS SODIUM) 500
GANCICLOVIR (AS SODIUM) 250 MG
GANCICLOVIR (AS SODIUM) 250 MG
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