A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
3,3'-Azobis[6-hydroxybenzoic Acid]
[A prodrug of mesalamine (5-Aminosalicylic acid; 5-ASA) with anti-inflammatory activity. Unabsorbed olsalazine passes through gastrointestinal tract and is cleaved by azoreductases, produced by microflora in colon, into 2 active molecules of 5-ASA. 5-ASA exerts its anti-inflammatory action locally by inhibiting cyclooxygenase and lipoxygenase activities, thereby reducing the production of prostaglandins and leukotrienes. In addition, mesalamine may act as a scavenger of reactive oxygen free radicals. ( NCI )]
UMLS (NCI) C0069454- Organic Chemical
- Pharmacologic Substance
Relation/PAR: Aminosalicylic Acids
[GA900] GASTRIC MEDICATIONS, OTHER
[GA900] GASTRIC MEDICATIONS, OTHER
Relation/CHD: Olsalazine Sodium
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