- 1. 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(2-Methylpropyl)-5-(2-propenyl)-
- [A barbiturate that exerts its effect by mimicking the inhibitory effect of gamma-aminobutyric acid (GABA) by binding to a site, distinct from the benzodiazepine binding site, on the GABA receptor. This leads to an increase in the duration of GABA-mediated opening of chloride channels and enhances the inhibitory effect of GABA. Consequently, its physiologic effects include sedation, hypnosis, reduction of anxiety, and respiratory depression and the drug causes tolerance and dependence. ( NCI )] (UMLS (NCI) C0054234) =Organic Chemical; Pharmacologic Substance =barbiturate;
[CN301] BARBITURIC ACID DERIVATIVE, SEDATIVES/HYPNOTICS =BUTALBITAL 50 MG;
BUTALBITAL 30 MG;
| - 2. 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-Ethyl-5-(1-methylbutyl), Monosodium Salt
- [The sodium salt of pentobarbital, a short-acting barbituric acid derivative with central nervous system (CNS) depressant property. Pentobarbital sodium binds to the gamma-aminobutyric acid (GABA)-A subtype receptor, resulting in modulation of chloride transport through receptor channels and potentiation of GABA-induced increases in chloride conductance. This enhances postsynaptic responses to the inhibitory actions of GABA and causes CNS depression. In addition, this agent inhibits glutamate induced nerve depolarization and depresses voltage-activated calcium currents. ( NCI )] (UMLS (NCI) C0700349) =Organic Chemical; Pharmacologic Substance ;
=PENTOBARBITAL;
=PENTOBARBITAL NA PWDR;
PENTOBARBITAL SODIUM 60 MG;
PENTOBARBITAL SODIUM 50 MG;
PENTOBARBITAL SODIUM 50 MG/ML;
PENTOBARBITAL SODIUM 30 MG;
PENTOBARBITAL SODIUM 120 MG;
PENTOBARBITAL SODIUM 100 MG;
PENTOBARBITAL SODIUM 200 MG;
PENTOBARBITAL SODIUM 20 MG/5ML |
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