[The acetate salt form of pirbuterol, a synthetic catecholamine and a pyridine derivative with sympathomimetic and bronchodilatory effects. Pirbuterol acetate selectively stimulates beta-2 adrenergic receptors, resulting in initiation of intracellular adenylate cyclase activity leading to increased levels of cAMP. As a result muscle relaxation (broncho- and vasodilation) occurs via cAMP-dependent signal transduction. In addition, elevated levels of cAMP inhibit release of inflammatory mediators from mast cells. ( NCI )]
UMLS (NCI) C0724666Pirbuterol Acetate
PIRBUTEROL ACETATE PREPARATION
- Organic Chemical
- Pharmacologic Substance
Relation/PAR: PIRBUTEROL
Relation/CHD: PIRBUTEROL ACETATE 0.2 MG/ACTUAT