HDAC4
[Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. This protein belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. (LocusLink) ( NCI )]
UMLS (NCI) C0910119HDAC-A
Histone Deacetylase 4
Histone Deacetylase A
Histone Deacetylase 4
Histone Deacetylase A
- Amino Acid, Peptide, or Protein
- Enzyme
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