HDAC1

1. [This gene plays a role in chromatin remodeling and the repression of gene expression. ( NCI )]
   UMLS (NCI) C1333891
   
   HDAC1 Gene
   Histone Deacetylase 1 Gene
    

   Gene or Genome
   

2. [Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. This protein belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. (LocusLink) ( NCI )]
   UMLS (NCI) C1334032
   
   Histone Deacetylase 1
    

   Amino Acid, Peptide, or Protein

   Enzyme