[Chemokine (C-C Motif) Receptor 8, encoded by the CCR8 gene, is a member of the beta chemokine receptor family and a seven transmembrane protein similar to G protein-coupled receptor. This receptor is expressed preferentially in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) are ligands of this receptor. This receptor and its ligands regulate monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. (From LocusLink and NCI) ( NCI )]
UMLS (NCI) C1307911
Chemokine (C-C Motif) Receptor 8
Chemokine (C-C) Receptor 8
Chemokine (C-C) Receptor-Like 2
CKRL1
CKR-L1
CMKBR8
CMKBRL2
CY6
GPR-CY6
TER1
- Amino Acid, Peptide, or Protein
- Receptor