- 1. C2B8 Monoclonal Antibody
- [A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells. ( NCI )] (UMLS (NCI) C0393022) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor =[AN000] ANTINEOPLASTICS;
Unclassified Ingredients =RITUXIMAB 10 MG/ML;
| - 10. CBF
- [CBF is an alpha/beta heterodimeric transcription factor involved in the transcriptional regulation of several genes important in hematopoiesis. The CBFalpha subunit binds directly to the enhancer core DNA sequence on target genes, whereas the beta subunit does not bind the DNA directly but increases the affinity and stabilizes the binding of the alpha subunit to the DNA. ( NCI )] (UMLS (NCI) C0212320) =Amino Acid, Peptide, or Protein; Biologically Active Substance
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- 2. C57BL
- (UMLS (NCI) C0025921) =Mammal ;
| - 11. CBFB
- [Part of the heterodimeric transcription factor Core-Binding Factor. CBF beta does not bind to DNA directly, but increases the affinity and stabilizes the binding of the CBF alpha (transcription factor AML1) for the CBF enhancer/promoter DNA site in TCR genes. CBF appears to regulate hematopoietic differentiation. Disruption of CBFB is associated with some leukemias. (from SWISS-PROT Q13951, OMIM 121360, and NCI) ( NCI )] (UMLS (NCI) C0526211) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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- 3. C6 Beta-Chemokine
- [Expressed in lung, liver, skeletal muscle, bone marrow, placenta, pancreas, and fetal liver by human CCL23 Gene (Intercrine Beta Family), secreted immunoregulatory Small Inducible Cytokine A23 Isoform Ckbeta8 is a potent CCR1 receptor agonist and suppressor of progenitor cell colony formation with chemotactic activity for resting T lymphocytes, monocytes, and neutrophils in inflammatory processes. ( NCI )] (UMLS (NCI) C0538072) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
| - 12. CBFB
- [This gene is involved in hematopoiesis and osteogenesis. ( NCI )] (UMLS (NCI) C1332671) CBFB Gene;
Core-Binding Factor, Beta Subunit Gene =Gene or Genome |
- 4. CB 1348
- (UMLS (NCI) C0729022) CB-1348;
=Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance | - 13. CBL
- [The cellular homologue of v-cbl, CBL protein is expressed in a range of hemopoietic lineages. Malignancies are associated with translocations of the CBL gene. Adaptor protein CBL2, containing a RING finger and multiple SH3 domains, encodes a protein similar to SLI1, a negative regulator of an EGF receptor tyrosine kinase homologue. Through its SH2 domain, CBL regulates activated tyrosine-phosphorylated receptor PTK ubiquitination as an E3 ubiquitin ligase and recruits, and activates, an E2 ubiquitin-conjugating enzyme through its RING domain. CBL is recruited to the tyrosine kinase insulin receptor by CAP adaptor protein, through a CAP SH3 domain. Upon CBL phosphorylation, CAP/CBL dissociates from the receptor to complex with caveolar flotillin and localize to plasma membrane lipid rafts. (from OMIM 165360 and NCI) ( NCI )] (UMLS (NCI) C1367374) CBL Gene Product;
CBL Protein;
CBL2 Gene Product =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 5. CB 1639
- (UMLS (NCI) C0728841) CB-1639 =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 14. CBLB
- [Cass-Br-M (Murine) Ecotropic Retroviral Transforming Sequence B (CBLB), encoded by the CALB gene, is a member of the CBL family of E3 ubiquitin ligases, which are critical negative regulators of tyrosine kinase signaling pathways in the immune system. Impairment of the CBLB signaling pathway may contribute to human autoimmune diseases, including type 1 diabetes. CBLB contains putative nuclear localization signal, zinc finger, leucine zipper, and proline-rich domains. It associates with three SH3 domain proteins FYN, FGR, and PLCG1. Three isoforms (a long form, truncated isoform 1, truncated isoform 2) are produced by alternative splicing. (From OMIM, PMID and NCI) ( NCI )] (UMLS (NCI) C1335961) Signal Transduction Protein CBLB =Amino Acid, Peptide, or Protein; Enzyme
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- 6. CB 304
- (UMLS (NCI) C0950953) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
| - 15. cBR96-Doxorubicin Immunoconjugate/Docetaxel
- (UMLS (NCI) C1134518) =Therapeutic or Preventive Procedure
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- 7. CB-3025
- (UMLS (NCI) C0733456) =Organic Chemical; Pharmacologic Substance ;
| - 16. cBR96-Doxorubicin Immunoconjugate/Gemcitabine
- (UMLS (NCI) C1327907) =Therapeutic or Preventive Procedure ;
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- 8. CB10-277
- [A synthetic derivative of dimethylphenyl-triazene related to dacarbazine, with antineoplastic properties. Related to the agent dacarbazine, CB10-277 is converted in vivo to a monomethyl triazene form that alkylates DNA, resulting in inhibition of DNA replication and repair; in addition, this agent may act as a purine analogue, resulting in inhibition of DNA synthesis, and may interact with protein sulfhydryl groups. (NCI04) ( NCI )] (UMLS (NCI) C0284098) =Organic Chemical; Pharmacologic Substance ;
| - 17. CBT
- [involves identifying and changing specific cognitive processes as they relate to problems of emotions and behavior; based on the premise that cognition, the process of acquiring knowledge and forming beliefs, is a primary determinant of mood and behavior; directed toward learning through practice of specific skills which have direct relevance to the present problem. ( CSP )] (UMLS (CSP) C0009244) =Therapeutic or Preventive Procedure =Behavior Conditioning Therapy;
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- 9. CBA
- (UMLS (NCI) C0025922) =Mammal ;
| - 18. CBT-1
- [An orally available natural product and a multiple-drug resistance (MDR) modulator with potential antineoplastic enhancing activity. CBT-1 enters and attaches to the inside of the MDR pump P-glycoprotein (P-gp), a member of the ATP-binding cassette superfamily of transmembrane transporters and overexpressed in some multi-drug resistant tumors. By attaching to P-gp, CBT-1 prevents the pump from working effectively and reverses the P-gp mediated cancer cell resistance to a variety of chemotherapeutic agents. ( NCI )] (UMLS (NCI) C0916470) MDR Modulator CBT-1 =Pharmacologic Substance; Biologically Active Substance ;
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