[Encoded by human DDX16 Gene (DEAD/H Subfamily, member 16), ubiquitous 1041-amino acid 119.3-kD nuclear DEAD/H Box Protein 16 is a functional homolog of the Prp8/cdc28 cell cycle progression protein (S. pombe), similar to DEAH box proteins that act as splicing factors. DBP2 is a probable ATP-binding RNA helicase involved in pre-mRNA splicing. DEAD box proteins, characterized by a conserved Asp-Glu-Ala-Asp (DEAD) motif, are putative RNA helicases that alter RNA secondary structure and influence translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on distribution, some family members may be involved in embryogenesis, spermatogenesis, and cellular growth and division. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )]
UMLS (NCI) C1333211DBP2
DDX16
DDX16 Protein
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 16
DEAD/H Box 16
DEAD/H Box Protein 16
DEAH-Box Protein 16
DEAH-Box Protein 2
PRP8 Homolog
Putative Pre-mRNA Splicing Factor RNA Helicase
- Amino Acid, Peptide, or Protein
- Biologically Active Substance