[The hydrochloride salt form of palonosetron, a carbazole derivative and a selective serotonin receptor antagonist with antiemetic properties. Palonosetron competitively blocks the action of serotonin at 5-HT3 receptors located on vagal afferents in the chemoreceptor trigger zone (CTZ), resulting in suppression of chemotherapy-induced nausea and vomiting. ( NCI )]
UMLS (NCI) C1310734PALONOSETRON HCL UNIDENTIFIED
PALONOSETRON HCL UNIDENTIFIED
PALONOSETRON HYDROCHLORIDE
- Organic Chemical
- Pharmacologic Substance