[The levoisomer of nordefrin, a synthetic catecholamine and norepinephrine derivative with sympathomimetic and antihypertensive effects. Levonordefrin's antihypertensive effect is exerted through activation of alpha 2-adrenergic receptors in the cardiovascular control center of the CNS thereby suppressing the sympathetic output from the brain and subsequently lowering blood pressure. Levonordefrin binds to and activates peripheral alpha 2- adrenergic receptors, thereby causing vasoconstriction. ( NCI )]
UMLS (NCI) C0520472 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: Nordefrin
[DE700] LOCAL ANESTHETICS, TOPICAL
Relation/CHD: LEVONORDEFRIN 1:20000