- 2401. InteractionDetectedIssueCode
- (UMLS (HL7) C1697994) =Intellectual Product =AppropriatenessDetectedIssueCode;
=Food Interaction Alert; Therapeutic Product Alert | - 2451. interferon resource
- [ ] (UMLS (CSP) C1328811) =Health Care Related Organization; ;
|
- 2402. Interactive Continuation
- (UMLS (HL7) C1547180) =Idea or Concept =Continuation style code;
| - 2452. Interferon Therapy
- (UMLS (NCI) C0279030) =Therapeutic or Preventive Procedure
|
- 2403. interactive multimedia
- [integration of audiovisual technology with computer simulated human interaction to control activities and monitor user responses to computer generated questions. ( CSP )] (UMLS (CSP) C0596785) =Intellectual Product ;
=computer human interaction; informatics | - 2453. Interfollicular Pattern
- (UMLS (NCI) C1334198) =Finding; ;
|
- 2404. interactive therapy
- [ ] (UMLS (CSP) C0872348) =Therapeutic or Preventive Procedure ;
| - 2454. intergenerational
- [ ] (UMLS (CSP) C0598500) =Temporal Concept ;
|
- 2405. InterameningealRoute
- [Interameningeal ( HL7V3.0 )] (UMLS (HL7) C1700023) =Functional Concept =RouteBySite;
=Injection, interameningeal; | - 2455. interhemispheric transfer
- [transfer of information between cerebral hemispheres. ( CSP )] (UMLS (CSP) C0596787) =Mental Process ;
=brain interhemispheric activity; |
- 2406. Interaretynoid Leukoplakia
- (UMLS (NCI) C0426552) =Neoplastic Process
| - 2456. InteriorSalish
- (UMLS (HL7) C1698103) =Language =Salishan;
=Okanagan; Flathead-Kalispel; Coeur D'alene; Columbian |
- 2407. INTERAT VEN RETRN TRANSP
- (UMLS (ICD9CM) C0392829) =Therapeutic or Preventive Procedure ;
| - 2457. Interleukin
- [(in-ter-LOO-kins) Biological response modifiers (substances that can improve the body's natural response to infection and disease) that help the immune system fight infection and cancer. These substances are normally produced by the body. They are also made in the laboratory for use in treating cancer and other diseases. ( NCI )] (UMLS (NCI) C0021764) =Amino Acid, Peptide, or Protein; Immunologic Factor
|
- 2408. Interatrial Septum
- [The thin membrane-like muscular structure separating the right and the left upper chambers (HEART ATRIA) of a heart. ( MSH )] (UMLS (NCI) C0225836) =Body Part, Organ, or Organ Component
| - 2458. Interleukin 1 Signal Transducer
- [Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas, human TRAF6 Gene (TRAF Family) encodes 522-aa 60-kDa oligomeric adapter protein and signal transducer TNF Receptor-Associated Factor 6, containing a MATH domain, a RING-type zinc finger, 2 TRAF-type zinc fingers, and a coiled coil domain that mediates homo- and hetero-oligomerization. The MATH/TRAF domain binds to receptor cytoplasmic domains. In mediating TNFR and Toll/IL-1 family signal transduction to diverse pathways, TRAF6 interacts with TNFRSF5, -11A, -11B, -16 and -17, SRC, PKC zeta, IRAK1, -2, and -3, RIPK2, MAP3K1, -5, and -14, CSK, TRIP, TRAF, TTRAP, PELI1, PELI2, and PELI3. TRAF6 activates IKK in the NF-kappa B pathway in response to proinflammatory cytokines and is involved in the IL-1 signaling pathway via MYD88 and IRAK kinases. (NCI) ( NCI )] (UMLS (NCI) C0530129) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 2409. intercalated disc
- [ ] (UMLS (CSP) C0684215) =Cell Component ;
| - 2459. Interleukin 12 Receptor
- [Human high affinity Interleukin 12 Receptor is composed of Interleukin 12 Receptor Beta 1 Chain (I12RB1) and Interleukin 12 Receptor Beta 2 Chain (IL12RB2), each a type I transmembrane disulfide-linked dimer/oligomer protein containing 5 FNIII domains, a box 1 motif required for JAK interaction/activation, and a WSXWS motif for protein folding, intracellular transport, and cell-surface receptor binding. Involved in IL12 signal transduction, IL12RB1 and IL12RB2 oligomers act as low affinity IL12 receptors. (NCI) ( NCI )] (UMLS (NCI) C0255732) =Amino Acid, Peptide, or Protein; Receptor ;
|
- 2410. Intercalated Duct of the Pancreas
- (UMLS (NCI) C0227577) =Body Part, Organ, or Organ Component
| - 2460. Interleukin Gene
- [Interleukin Genes encode Interleukins, soluble cytokine factors produced by leukocytes and other cell types that have broad functional activities, particularly in regulating the inflammatory and immune responses of a variety of cell types. Interleukins enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules, and responses to immune and inflammatory stimuli. (NCI) ( NCI )] (UMLS (NCI) C1334205) =Gene or Genome; ;
|
- 2411. Intercalated Neuron
- [generally neurons which are not motor or sensory; may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. ( CSP )] (UMLS (NCI) C0021792) =Cell ;
=nerve cell; | - 2461. interleukin receptor
- [Cell surface proteins that bind interleukins and trigger intracellular changes influencing the behavior of cells. ( MSH )] (UMLS (CSP) C0206553) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
|
- 2412. intercellular cementing substance
- [ ] (UMLS (CSP) C0596786) =Body Substance ;
| - 2462. Interleukin Therapy
- (UMLS (NCI) C0281177) =Therapeutic or Preventive Procedure
|
- 2413. intercellular connection
- [direct contact and connection of a cell with a neighboring cell. ( CSP )] (UMLS (CSP) C0178718) =Body Space or Junction ;
=Cellular Biology; =synapse; Communicating Junction; Occluding Junction; | - 2463. Interleukin-1 Receptor-Associated Kinase 1
- [Encoded by human IRAK1 Gene (Pelle Ser/Thr Kinase Family), ubiquitous 712-aa 77-kDa Interleukin-1 Receptor-Associated Kinase 1 is one of two putative Ser/Thr kinases that rapidly associate with the Interleukin-1 Receptor (IL1R) upon stimulation. IRAK phosphorylation occurs after association with IL1-R-1, which may activate the kinase. Found in a complex containing TRAF6, PELI1 and IRAK4, IRAK1 interacts with PELI2 and PELI3. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. (NCI) ( NCI )] (UMLS (NCI) C1334201) IRAK1;
IRAK-1; Pelle Homolog; =Amino Acid, Peptide, or Protein; Enzyme; Immunologic Factor |
- 2414. Intercept
- [ ] (UMLS (CSP) C0598981) =Organic Chemical; Pharmacologic Substance
| - 2464. Interleukin-1 Receptor-Associated Kinase 1 Gene
- [This gene plays a role in signal transduction and the immune response. ( NCI )] (UMLS (NCI) C1334134) IRAK1;
IRAK1 Gene =Gene or Genome ; |
- 2415. Intercostal Artery
- (UMLS (NCI) C0459917) =Body Part, Organ, or Organ Component ;
| - 2465. Interleukin-1 Receptor-Associated Kinase 2
- [Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas, and peripheral leukocytes by human IRAK2 Gene (Pelle Ser/Thr Kinase Family), 590-aa 65-kDa Interleukin-1 Receptor-Associated Kinase 2 is one of two putative Ser/Thr kinases that rapidly associate with the Interleukin-1 Receptor (IL1R) upon stimulation. IRAK2 interacts with TRAF6 and is required for IL1R-induced NF-Kappa-B activation. (NCI) ( NCI )] (UMLS (NCI) C0663246) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 2416. intercostal muscle
- [Respiratory muscles that arise from the lower border of one rib and insert into the upper border of the adjoining rib, and contract during inspiration or respiration. (From Stedman, 25th ed) ( MSH )] (UMLS (CSP) C0021724) =Body Part, Organ, or Organ Component
| - 2466. Interleukin-1 Receptor-Associated Kinase 2 Gene
- [This gene is involved in the immune response and signal transduction. ( NCI )] (UMLS (NCI) C1334135) IRAK2;
IRAK2 Gene =Gene or Genome ; |
- 2417. Intercostal Nerve
- [The ventral rami of the thoracic nerves from segments T1 through T11. The intercostal nerves supply motor and sensory innervation to the thorax and abdomen. The skin and muscles supplied by a given pair are called, respectively, a dermatome and a myotome. ( MSH )] (UMLS (NCI) C1285089) =Body Part, Organ, or Organ Component
| - 2467. Interleukin-1 Receptor-Associated Kinase 3
- [Expressed in peripheral leukocytes and monocytes by human IRAK3 Gene, 596-aa Interleukin-1 Receptor-Associated Kinase 3 contains an N-terminal death domain and central kinase domain. IRAK3 appears to activate NF-kappa-B via IL1R. IRAK3 interacts with MYD88 and TRAF6 signaling proteins in a manner similar to the other IRAKs. It prevents dissociation of IRAK and IRAK4 from MYD88 and formation of IRAK/TRAF6 complexes. But IRAK3 does not autophosphorylate in the manner of IRAK1. IRAK1, -2, and -3 mediate the TLR2-dependent response to lipopolysaccharide. IRAK3 is induced upon TLR stimulation and negatively regulates TLR signaling. (NCI) ( NCI )] (UMLS (NCI) C1334202) Interleukin-1 Receptor-Associated Kinase M;
IRAK3; IRAKM; =Amino Acid, Peptide, or Protein; Enzyme ; |
- 2418. Interdigital Nerve Scar
- (UMLS (NCI) C0311337) =Disease or Syndrome
| - 2468. Interleukin-1 Receptor-Associated Kinase 3 Gene
- [This gene is involved in signal transduction and the immune response. ( NCI )] (UMLS (NCI) C1334136) IRAK3;
IRAK3 Gene =Gene or Genome ; |
- 2419. interdisciplinary collaboration
- [working with others as a team involving medical research and/or patient care. ( CSP )] (UMLS (CSP) C0597720) =Health Care Activity ;
=health care service planning; health science research | - 2469. Interleukin-1 Receptor-Associated Kinase 4
- [Widely expressed (strongest in kidney and liver) by human IRAK4 Gene, 460-aa Interleukin-1 Receptor-Associated Kinase 4 contains (like IRAK1, IRAK2, IRAKM, and Pelle) an N-terminal death domain and a central kinase domain. Similar to Pelle, IRAK4 has a short C-terminal domain. Like all IL1R-associated kinases, IRAK4 mediates Toll/IL1R family receptor signal transduction. Like IRAK1 and Pelle, IRAK4 has auto- and cross-phosphorylation activity. IRAK4 phosphorylates and activates IRAK1. It also interacts with MYD88 and TRAF6 and activates MAPK and NF kappa-B pathways. IRAK4 may act as an IRAK1 kinase, triggering phosphorylation cascades. (NCI) ( NCI )] (UMLS (NCI) C1334203) IRAK4;
REN64 =Amino Acid, Peptide, or Protein; Enzyme ; |
- 2420. Interdisciplinary Research
- [Studies that bring together multiple scientific disciplines to address specific issues. ( NCI )] (UMLS (NCI) C0242479) =Occupational Activity ;
| - 2470. Interleukin-1 Receptor-Associated Kinase 4 Gene
- [This gene plays a role in signal transduction and the immune response. ( NCI )] (UMLS (NCI) C1334137) IRAK4;
IRAK4 Gene; =Gene or Genome ; |
- 2421. interest
- [A state of curiosity or concern about or attention to something; to be of importance or consequence. ( NCI )] (UMLS (CSP) C0543488) =Mental Process ;
| - 2471. Interleukin-12/MART-1 Antigen/Montanide ISA-51
- (UMLS (NCI) C0879330) =Therapeutic or Preventive Procedure
|
- 2422. Interest Rate Code
- (UMLS (HL7) C1550363) =Intellectual Product =HL7 Vocabulary Version 2.5;
| - 2472. Interleukin-12/Montanide ISA-51/Tyrosinase Peptide
- (UMLS (NCI) C0879316) =Therapeutic or Preventive Procedure
|
- 2423. interference microscopy
- [microscopy utilizing a direct beam of light which splits and recombines as it passes through the specimen, forming a pattern that corresponds to variations in the specimen's thickness and refraction; used to examine transparent objects such as living cells. ( CSP )] (UMLS (CSP) C0026023) =Laboratory Procedure ;
=microscopy; | - 2473. Interleukin-12/Montanide ISA-51/Tyrosinase Related Protein-1
- (UMLS (NCI) C0879322) Interleukin-12/Montanide ISA-51/Tyrosinase-Related Protein-1 =Therapeutic or Preventive Procedure
|
- 2424. interfering virus
- [a virus which prevents replication of another virus; may be due to blocking of virus attachment sites or the presence of defective interfering particles which block the replication of competent ones. ( CSP )] (UMLS (CSP) C0042730) =Natural Phenomenon or Process ;
=virus characteristic; | - 2474. Interleukin-12/Paclitaxel
- (UMLS (NCI) C1327862) =Therapeutic or Preventive Procedure
|
- 2425. interferometry
- [measurement of distances or movements by means of the phenomena caused by the interference of two rays of light. ( CSP )] (UMLS (CSP) C0021730) =Laboratory Procedure =Optical;
| - 2475. Interleukin-12/Paclitaxel/Trastuzumab
- (UMLS (NCI) C1134712) =Therapeutic or Preventive Procedure
|
- 2426. Interferon Alfa
- [A highly purified alpha interferon produced by a human lymphoid cell line. Interferon alpha-n1 consists of multiple alpha interferon subtypes, at least two of which are glycosylated. In contrast, recombinant alpha interferons are individual non-glycosylated proteins produced from individual alpha interferon genes. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose proteins have antiviral, antiproliferative, anticancer, and immune-modulating effects. (NCI04) ( NCI )] (UMLS (NCI) C0699817) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 2476. Interleukin-12/PSA Prostate Cancer Vaccine
- (UMLS (NCI) C0935836) =Therapeutic or Preventive Procedure
|
- 2427. Interferon Alfa/Isotretinoin/Paclitaxel
- (UMLS (NCI) C0879497) =Therapeutic or Preventive Procedure ;
| - 2477. Interleukin-12/Rituximab
- (UMLS (NCI) C0879417) =Therapeutic or Preventive Procedure
|
- 2428. Interferon Alfa/Lamivudine/Zidovudine
- (UMLS (NCI) C1134708) =Therapeutic or Preventive Procedure ;
| - 2478. Interleukin-2 Liposome
- [A formulation in which liposomes are loaded with the cytokine interleukin-2 (IL-2). By activating cytotoxic T-lymphocytes, such as lymphokine-activated killer cells, and increasing levels of the cytotoxic cytokines interferon-gamma (IFN-gamma) and transforming growth factor-beta (TGF-beta), IL-2 may exhibit antitumoral activity. Liposomal formulations of IL-2 may promote entry of the cytokine into target tumor cells and may be used as an immunoadjuvant in cancer vaccine therapy. (NCI04) ( NCI )] (UMLS (NCI) C0281031) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 2429. Interferon Alfa/Lutetium Lu 177 Monoclonal Antibody CC49/Paclitaxel
- (UMLS (NCI) C0935676) =Therapeutic or Preventive Procedure
| - 2479. Interleukin-2/interleukin-12
- (UMLS (NCI) C0879476) =Therapeutic or Preventive Procedure ;
|
- 2430. Interferon Alfa/Lutetium Lu 177 Monoclonal Antibody CC49/Topotecan
- (UMLS (NCI) C0935677) =Therapeutic or Preventive Procedure
| - 2480. Interleukin-2/Isotretinoin/Monoclonal Antibody Ch14.18
- (UMLS (NCI) C1134513) =Therapeutic or Preventive Procedure
|
- 2431. Interferon Alfa/Lymphokine-Activated Killer Cells
- (UMLS (NCI) C0935848) =Therapeutic or Preventive Procedure
| - 2481. Interleukin-2/MAGE-12 Peptide Vaccine/Montanide ISA-51
- (UMLS (NCI) C0935672) =Therapeutic or Preventive Procedure
|
- 2432. Interferon Alfa/Oblimersen
- (UMLS (NCI) C1327948) =Therapeutic or Preventive Procedure; ;
| - 2482. Interleukin-2/Monoclonal Antibody Ch14.18
- (UMLS (NCI) C0935880) =Therapeutic or Preventive Procedure
|
- 2433. Interferon Alfa/Paclitaxel/Yttrium Y 90 Monoclonal Antibody CC49
- (UMLS (NCI) C0935678) =Therapeutic or Preventive Procedure
| - 2483. Interleukin-2/Montanide ISA-51/Telomerase: 540-548 Peptide Vaccine
- (UMLS (NCI) C0935897) =Therapeutic or Preventive Procedure
|
- 2434. Interferon Alfa/SU5416
- (UMLS (NCI) C0935695) =Therapeutic or Preventive Procedure
| - 2484. Interleukin-2/Montanide ISA-51/Tyrosinase Peptide
- (UMLS (NCI) C0879315) =Therapeutic or Preventive Procedure
|
- 2435. Interferon Alfa/Temozolomide
- (UMLS (NCI) C1134620) =Therapeutic or Preventive Procedure ;
| - 2485. Interleukin-2/Montanide ISA-51/Tyrosinase-Related Protein-1
- (UMLS (NCI) C0879321) =Therapeutic or Preventive Procedure
|
- 2436. Interferon Alfa/Thalidomide
- (UMLS (NCI) C0879569) =Therapeutic or Preventive Procedure
| - 2486. Interleukin-2/Montanide ISA-51/Tyrosinase-Related Protein-2
- (UMLS (NCI) C1134466) =Therapeutic or Preventive Procedure
|
- 2437. Interferon Alpha Receptor
- [Human Interferon Alpha Receptor Complex (Type II Cytokine Family Receptor) is a ubiquitous type I membrane protein heteromeric receptor for type I IFNs, alpha and beta, composed of at least 2 chains, IFNAR1 (alpha chain) and IFNAR2 (beta chain). In mediating innate immune responses to viral infection and specific interferon inhibition of virus replication, binding of alpha and beta IFNs triggers tyrosine phosphorylation of JAKs, TYK2, STAT proteins, autophosphorylation, and tyrosine phosphorylation by TYK2. (NCI) ( NCI )] (UMLS (NCI) C0248648) =Amino Acid, Peptide, or Protein; Receptor ;
| - 2487. Interleukin-2/Montanide ISA-51/Von Hippel-Lindau Peptide Vaccine
- (UMLS (NCI) C0879309) =Therapeutic or Preventive Procedure
|
- 2438. interferon beta 1b
- [ ] (UMLS (CSP) C0244713) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor =[IM700] IMMUNE STIMULANTS;
Beta Interferon =Beta-ser-interferon | - 2488. Interleukin-2/p53 Peptide Vaccine
- (UMLS (NCI) C1327823) =Therapeutic or Preventive Procedure ;
|
- 2439. Interferon Beta-1A
- [A synthetic version of naturally occuring interferons that have immunomodulatory, antiviral and antiproliferative activities. It may exert antitumor activity by anti-angiogenic and cell differentiation activities. (NCI) ( NCI )] (UMLS (NCI) C0982234) INTERFERON BETA-1A,RECOMBINANT;
INTERFERON BETA-1A,RECOMBINANT PREPARATION; Recombinant interferon beta-1a =Amino Acid, Peptide, or Protein; Pharmacologic Substance =interferon beta 1a; =INTERFERON BETA-1A,RECOMBINANT 22 MCG/0.5ML; INTERFERON BETA-1A,RECOMBINANT 30 MCG/0.5ML; INTERFERON BETA-1A,RECOMBINANT 44 MCG/0.5ML; INTERFERON BETA-1A,RECOMBINANT 30 MCG; | - 2489. Interleukin-2/Staphylococcal Enterotoxin B
- (UMLS (NCI) C0879542) =Therapeutic or Preventive Procedure ;
|
- 2440. Interferon Gamma/Voriconazole
- (UMLS (NCI) C1327961) =Therapeutic or Preventive Procedure; ;
| - 2490. Interleukin-2/Stem Cell Factor
- (UMLS (NCI) C0879556) =Therapeutic or Preventive Procedure
|
- 2441. interferon inducer
- [agents that promote the production and release of interferons; they include mitogens, lipopolysaccharides, and the synthetic polymers Poly A-U and Poly I-C; viruses, bacteria, and protozoa have been also known to induce interferons. ( CSP )] (UMLS (CSP) C0021742) =Pharmacologic Substance; Immunologic Factor ;
=[AM800] ANTIVIRALS; biological response modifier; immunomodulator; =5'-Inosinic Acid, Homopolymer Complex with 5'-Cytidylic Acid Homopolymer; | - 2491. Interleukin-2/Trastuzumab
- (UMLS (NCI) C0935669) =Therapeutic or Preventive Procedure
|
- 2442. interferon receptor
- [Specific molecular sites or structures on or in cells with which interferons react or to which they bind in order to modify the function of the cells. Interferons exert their pleiotropic effects through two different receptors. alpha- and beta-interferon crossreact with common receptors, while gamma-interferon initiates its biological effects through its own specific receptor system. ( MSH )] (UMLS (CSP) C0063699) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
| - 2492. Interleukin-2/Vaccine-Sensitized Draining Lymph Node Cells
- (UMLS (NCI) C0879356) =Therapeutic or Preventive Procedure ;
|
- 2443. interferon registry
- [ ] (UMLS (CSP) C1331080) =Health Care Related Organization
| - 2493. Interleukin-2/Vaccinia-Tyrosinase Vaccine
- (UMLS (NCI) C0796659) =Therapeutic or Preventive Procedure
|
- 2444. Interferon Regulatory Factor 1 Gene
- [This gene plays a role in the transcriptional activation of target genes. It is also involved in promoting apoptosis. ( NCI )] (UMLS (NCI) C1366516) IRF1;
IRF1 Gene =Gene or Genome | - 2494. Interlobular Bile Duct
- (UMLS (NCI) C0227515) =Body Part, Organ, or Organ Component
|
- 2445. Interferon Regulatory Factor 2
- [Encoded by human IRF2 Gene (IRF Family), transcription factor Interferon Regulatory Factor 2 competitively inhibits IRF1-transcriptional activation of interferons alpha and beta, and perhaps other IRF1-activated genes. IRF2 also functions as a transcriptional activator of histone H4. (NCI) ( NCI )] (UMLS (NCI) C1506302) IRF2;
=Amino Acid, Peptide, or Protein; Biologically Active Substance ; | - 2495. Interlocutory
- [Subject to an Interlocutory Decree. ( HL7V3.0 )] (UMLS (HL7) C1549108) =Finding =marital status;
MaritalStatus |
- 2446. Interferon Regulatory Factor 2 Gene
- [This gene is involved in the repression of IRF1-activated transcription. It also plays a role in the transcriptional activation of target genes. ( NCI )] (UMLS (NCI) C1334138) IRF2;
IRF2 Gene; =Gene or Genome ; | - 2496. Intermediary Metabolism
- [sum of chemical changes that occur within the tissues of an organism consisting of anabolism (biosynthesis) and catabolism; the buildup and breakdown of molecules for utilization by the organism. ( CSP )] (UMLS (NCI) C0025519) =Organism Function =biochemistry;
Elimination =bioenergetics; biotransformation; anabolism; aerobic metabolism; carbohydrate metabolism; bioaccumulation; aminoacid metabolism; bone metabolism; brain metabolism; connective tissue metabolism; heart metabolism; hormone metabolism; metal metabolism; microorganism metabolism; muscle metabolism; neurotransmitter metabolism; nitrogen metabolism; nucleic acid metabolism; Metabolism, Purines/Pyrimidines/Nucleotides/Nucleic Acids; phosphorus metabolism; porphyrin metabolism; protein metabolism; purine/pyrimidine metabolism; toxin metabolism; vitamin metabolism; fat metabolism; basal metabolism; drug metabolism; measurement of metabolism; Hepatic Metabolism; kidney metabolism; Site of Metabolism; Enzymatic Pathway of Metabolism; |
- 2447. Interferon Regulatory Factor 3
- [IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. (from LocusLink) ( NCI )] (UMLS (NCI) C0384768) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 2497. intermediate
- [Intermediate ( HL7V3.0 )] (UMLS (HL7) C1550465) =Idea or Concept =ObservationInterpretationSusceptibility;
|
- 2448. Interferon Regulatory Factor 3 Gene
- [This gene plays a role in the transcriptional activation of target genes. ( NCI )] (UMLS (NCI) C1334139) IRF3;
IRF3 Gene; =Gene or Genome ; | - 2498. Intermediate Blood Vessel Neoplasm
- [A borderline blood vessel neoplasm that can be locally aggressive, and may metastasize on rare occasions. ( NCI )] (UMLS (NCI) C1334207) Intermediate Blood Vessel Tumor =Neoplastic Process; ;
|
- 2449. Interferon Regulatory Factor 4
- [Interferon regulatory factor 4 is a transcriptional activator that binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter and to the immunoglobulin lambda light chain enhancer, together with PU.1. IRF4 probably plays a role in the ISRE-targeted signal transduction mechanisms of lymphoid cells. Two isoforms are produced by alternative splicing. (from OMIM 601900 and NCI) ( NCI )] (UMLS (NCI) C0299544) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 2499. Intermediate Care Facility, Mentally Retarded
- [(1) A public institution for care of the mentally retarded or people with related conditions. (2) An institution giving active treatment to mentally retarded or developmentally disabled persons or persons with related conditions. The primary purpose of the institution is to provide health or rehabilitative services to such individuals.Sources: (1) Lexikon: Dictionary of Health Care Terms, Organizations and Acronyms for the Era of Reform, Joint Commission on Accreditation of Healthcare Organizations, Oakbrook Terrace, IL: 1994, p. 403 (2) Paraphrased from Code of Federal Regulations #42, Public Health, Section 440.150(c). ( HL7V3.0 )] (UMLS (HL7) C1552484) =Intellectual Product ;
=Nursing and Custodial Care Facilities; |
- 2450. Interferon Regulatory Factor 4 Gene
- [This gene is involved in the regulation of B-cell differentiation and proliferation. It also plays a role in mediating the proliferation of mitogen-stimulated T cells. ( NCI )] (UMLS (NCI) C0812314) IRF4;
IRF4 Gene =Gene or Genome ; | - 2500. Intermediate Care, Mental Illness
- [A nursing facility that provides an intermediate level of nursing care to individuals whose functional abilities are significantly compromise by mental illness. ( HL7V3.0 )] (UMLS (HL7) C1552539) =Intellectual Product ;
=Nursing and Custodial Care Facilities; |