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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
I I- I0 I1 I2 I3 I4 I5 I6 I7 I8 I9 IA IB IC ID IE IF IG IH II IK IL IM IN IO IP IQ IR IS IT IU IV IX
IN INA INB INC IND INE INF ING INH INI INJ INK INL INM INN INO INP INR INS INT INU INV

Interleukin-1 Receptor-Associated Kinase 1

[Encoded by human IRAK1 Gene (Pelle Ser/Thr Kinase Family), ubiquitous 712-aa 77-kDa Interleukin-1 Receptor-Associated Kinase 1 is one of two putative Ser/Thr kinases that rapidly associate with the Interleukin-1 Receptor (IL1R) upon stimulation. IRAK phosphorylation occurs after association with IL1-R-1, which may activate the kinase. Found in a complex containing TRAF6, PELI1 and IRAK4, IRAK1 interacts with PELI2 and PELI3. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. (NCI) ( NCI )]
UMLS (NCI) C1334201
IRAK1
IRAK-1
Pelle Homolog
 
Amino Acid, Peptide, or Protein
Enzyme
Immunologic Factor
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