[Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas, and peripheral leukocytes by human IRAK2 Gene (Pelle Ser/Thr Kinase Family), 590-aa 65-kDa Interleukin-1 Receptor-Associated Kinase 2 is one of two putative Ser/Thr kinases that rapidly associate with the Interleukin-1 Receptor (IL1R) upon stimulation. IRAK2 interacts with TRAF6 and is required for IL1R-induced NF-Kappa-B activation. (NCI) ( NCI )]
UMLS (NCI) C0663246 - Amino Acid, Peptide, or Protein
- Enzyme