- 1. 3-(p-(bis(2-chloroethyl)amino)phenyl)-L-Alanine, Hydrochloride
- [A bifunctional alkylating agent and phenylalanine derivative of nitrogen mustard. Melphalan hydrochloride is converted into highly reactive ethylenimmonium intermediates that induce covalent guanine N7-N7 intra- and inter-crosslinks and alkylation of adenine N3 of DNA. This agent also alkylates RNA and protein structures. As a result RNA transcription and protein synthesis are inhibited, ultimately leading to cell growth arrest and/or death. ( NCI )] (UMLS (NCI) C0771055) Melphalan Hydrochloride;
MELPHALAN HYDROCHLORIDE PREPARATION =Organic Chemical; Pharmacologic Substance =4-[bis(2-chloroethyl)amino]-L-phenylalanine;
=MELPHALAN HYDROCHLORIDE 50 MG;
| - 2. PBI (protein bound iodine)
- [ ] (UMLS (CSP) C0033676) =Laboratory Procedure
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