- 1. PK1
- (UMLS (NCI) C0701488) =Organic Chemical; Pharmacologic Substance
| - 4. PKCA
- [Encoded by human PRKCA Gene (PKC Family), 672-aa 77-kDa Protein Kinase C-alpha is a calcium-activated (likely by the C2 domain), DAG-activated, phospholipid-dependent serine/threonine kinase containing 2 zinc-dependent phorbol-ester/DAG binding domains and a C2 domain that phosphorylates a range of cellular proteins. DAG markedly increases PKC sensitivity to calcium and phospholipids. PKC activation appears to be central in the induction of cellular responses to many ligand-receptor systems and to external stimuli. After GPCR stimulation, and triggered by PKC-dependent serine phosphorylation, RKIP dissociates from RAF1 to associate with and block GRK2 activity. By activating PKC, the receptor signal may be enhanced by removing a RAF1 inhibitor and blocking receptor internalization. A receptor for phorbol ester tumor promoters, PKC may interact with PRKCABP. (NCI) ( NCI )] (UMLS (NCI) C0256371) =Amino Acid, Peptide, or Protein; Enzyme ;
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- 2. PKC
- [nonEC. ( CSP )] (UMLS (NCI) C0033634) =Amino Acid, Peptide, or Protein; Enzyme ;
=alcohol phosphotransferase;
| - 5. PKI166
- [A pyrrolo-pyrimidine epidermal growth factor receptor (EGFR) protein kinase inhibitor with anti-tumor activity.PKI-166 reversibly inhibits HER1 and HER2 tyrosine kinases, belong to the epidermal growth factor receptor family, thereby inhibiting tumor growth and metastasis. ( NCI )] (UMLS (NCI) C0915195) =Organic Chemical; Pharmacologic Substance ;
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- 3. PKC412
- [A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called protein kinase C (PKC) inhibitors. ( NCI )] (UMLS (NCI) C0915830) PKC-412;
=Organic Chemical; Pharmacologic Substance ;
| - 6. PKS enzyme
- [group of enzymes functionally and structurally resembling the fatty acid synthase complex of microorganisms which produce the benzoisochromane quinone moiety of some antibiotics. ( CSP )] (UMLS (CSP) C0071598) =Amino Acid, Peptide, or Protein; Enzyme ;
=enzyme complex;
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