UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM - Terms starting with ‘B’

Dictionaries Armenian-English English-Armenian MeSH Feedback

UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM

%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

C C- C1 C3 C5 C6 C7 CA CB CC CD CE CF CG CH CI CJ CK CL CM CN CO CP CQ CR CS CT CU CV CW CX CY CZ

CXB CXC CXP

selected terms: 1

page 1 of 1

1. 520C9x22 Bispecific Antibody: [A partially humanized bivalent antibody targeting cytotoxic effector cells expressing Fc gamma receptor type I (Fc gammaRI, or CD64) against HER2/neu-overexpressing tumor cells. Bispecific antibody MDX-H210 was constructed by chemically linking Fab' fragments of the anti-HER2/neu-specific monoclonal antibody, 520C9, and the Fab' fragments of the anti-Fc gammaRI-specific monoclonal antibody, H22. While HER2/neu is overexpressed in a variety of malignancies, expression of Fc gammaRI is limited primarily to cytotoxic immune cells, including monocytes, macrophages, and cytokine-activated polymorphonuclear (PMN) cells. Therefore, HER2/neu expressing tumor cells bound by MDX-H210 can be selectively recognized by effector cells and triggers antibody-dependent cell-mediated cytotoxicity (ADCC), resulting in tumor cell lysis. ( NCI )] (UMLS (NCI) C0281736) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor

Buy website

Medical Clinic. Optician. Pharmacy. Physician. Travel Agency. Hotel reservation. Child Care. Education. Teachers. Lessons. Tests and Exams. Certification. Shopping Center. Store. Real Estate.
Affordable prices from $100.