[The hydrochloride salt form of midodrine, a direct-acting prodrug and sympathomimetic agent with antihypotensive properties. Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier, and is therefore not associated with effects on the central nervous system. ( NCI )]
UMLS (NCI) C07333941-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol Hydrochloride
MIDODRINE HYDROCHLORIDE
MIDODRINE HYDROCHLORIDE PREPARATION
Midodrine Monohydrochloride
- Organic Chemical
- Pharmacologic Substance
Relation/PAR: MIDODRINE
Relation/CHD: MIDODRINE HYDROCHLORIDE 2.5 MG
MIDODRINE HYDROCHLORIDE 5 MG
MIDODRINE HYDROCHLORIDE 10 MG