- 201. 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid
- [A topical retinoid-like compound, chemically similar to vitamin A. Although the exact mechanism of action is unknown, adapalene binds to specific retinoic acid receptors in the nucleus, leading to specific gene expression. This agent stimulates skin growth through modulation of cellular differentiation, inflammatory processes and keratinization of follicular epithelial cells. Adapalene may increase dermal sensitivity to ultraviolet radiation. (NCI04) ( NCI )] (UMLS (NCI) C0165631) =Organic Chemical; Pharmacologic Substance =naphthalene;
[DE752] ANTIACNE AGENTS, TOPICAL =ADAPALENE 0.1 % | - 251. A product from a reserve sample was evaluated
- (UMLS (HL7) C1546984) =Idea or Concept =Product source;
|
- 202. 6-Acetamido-4-methyl-1,2-dithiolo(4,3-b)pyrrol-5(4H)-one
- (UMLS (NCI) C0050460) =Organic Chemical; Pharmacologic Substance
| - 252. A product from the same lot as the actual product involved was evaluated
- (UMLS (HL7) C1546982) =Idea or Concept =Product source;
|
- 203. 6-Aminocaproic Acid
- [A synthetic lysine derivative with antifibrinolytic activity. Aminocaproic acid competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin (fibrinolysin), an enzyme that degrades fibrin clots as well as fibrinogen and other plasma proteins including the procoagulant factors V and VIII. Aminocaproic acid competitively reduces the conversion of plasminogen to plasmin by plasminogen activators. It directly inhibits proteolytic activity of plasmin, but higher doses are required than are needed to reduce plasmin formation. Aminocaproic acid is used in the treatment of hemorrhage and prophylactically against hemorrhage, including hyperfibrinolysis-induced hemorrhage and postsurgical hemorrhage. ( NCI )] (UMLS (NCI) C0000608) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 253. A race-based population
- (UMLS (HL7) C1548149) =Idea or Concept =Nature of Abnormal Testing;
|
- 204. 6a
- [Maxillary right canine abutment ( HL7V3.0 )] (UMLS (HL7) C1553638) =Medical Device =Artificial dentition;
| - 254. A request for a tentative (e.g., "penciled in") appointment
- (UMLS (HL7) C1548407) =Idea or Concept =Appointment Type Codes;
|
- 205. 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-Diacetate
- [The acetate salt form of diflorasone, a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorticoid receptor (GR) in the cytoplasm. The receptor complex subsequently translocates to the nucleus and activates or represses genes by interacting with short, palindromic DNA sequences called glucocorticoid response element (GRE). Gene activation leads to the exertion of anti-inflammatory effects, e.g. upregulation of IkappaB, while gene repression inhibits production of pro-inflammatory cytokines such as interleukin-1 (IL-1), IL-2 and IL-6, thereby preventing activation of cytotoxic T-lymphocytes. ( NCI )] (UMLS (NCI) C0057992) =Steroid; Pharmacologic Substance ;
=BETAMETHASONE;
DIFLORASONE =DIFLORASONE DIACETATE 0.05 %;
| - 255. A request to add a completed appointment, used to maintain records of completed appointments that did not appear in the schedule (e.g., STAT, walk-in, etc.)
- (UMLS (HL7) C1548405) =Intellectual Product =Appointment Type Codes;
|
- 206. 6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione, cyclic 16,17-acetal with Acetone
- [A synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Flurandrenolide exerts its effects by interacting with specific cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. ( NCI )] (UMLS (NCI) C0016374) =Steroid; Pharmacologic Substance; Hormone =Pregnenediones;
Steroids, Fluorinated;
[DE200] ANTI-INFLAMMATORY, TOPICAL;
=FLURANDRENOLIDE 4 MCG/SQC;
FLURANDRENOLIDE 0.05 %;
FLURANDRENOLIDE 0.025 %;
| - 256. A routine check-up, such as an annual physical
- (UMLS (HL7) C1548400) =Intellectual Product =Appointment reason codes;
|
- 207. 6alpha-Methyl-11-oxoprogesterone
- [The basic, partial chemical structure of corticosteroid hormones such as cortisone and aldosterone. (NCI04) ( NCI )] (UMLS (NCI) C0099478) =Organic Chemical; Pharmacologic Substance ;
| - 257. A sex-based population
- (UMLS (HL7) C1548150) =Idea or Concept =Nature of Abnormal Testing;
|
- 208. 7-(alpha-(4-Pyridylthio)acetamido)cephalosporanic acid sodium salt
- [The sodium salt form of cephapirin, a semi-synthetic, broad-spectrum, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephapirin sodium inhibits bacterial cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis and subsequent cross-linking of peptidoglycan units. This results in a reduction of cell wall stability and leads to cell lysis. ( NCI )] (UMLS (NCI) C0085905) =Organic Chemical; Antibiotic =7-(D-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)-oct-2-ene-2-caboxylic Acid;
=cephapirin 1 gm injectable powder for injection | - 258. A therapeutic substitution was dispensed.
- (UMLS (HL7) C1549559) =Idea or Concept =Substitution Status;
|
- 209. 7-Allyl-8-oxoguanosine
- [A guanine ribonucleotide derivative with immunostimulatory and immunomodulatory activity. Loxoribine undergoes facilitated transport across the plasma membrane into the cytoplasmic compartment of the cell and acts intracellularly, bypassing the biochemical steps involved in the membrane signal transduction pathway used by Ag or anti-IgM Abs to activate B cells. This agent activates the Toll-like receptor 7 (TLR7), a member of the TLR family of pathogen-associated molecular pattern recognition receptors thereby activating the innate immune system. This activation requires endosomal maturation and recognition is restricted to TLR7. As a result, loxoribine induces cycling B cells to proliferate and differentiate non-specifically and recruit antigen-reactive B cells to undergo differentiation to antibody production, markedly amplifying the underlying response in the process. ( NCI )] (UMLS (NCI) C0209660) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance; Immunologic Factor
| - 259. A'ananin
- (UMLS (HL7) C1555606) Ahahnelin;
=Language =ArapahoGrosVentre;
|
- 210. 7a
- [Maxillary right lateral incisor abutment ( HL7V3.0 )] (UMLS (HL7) C1553639) =Medical Device =Artificial dentition;
| - 260. A-43818
- (UMLS (NCI) C0701460) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hormone
|
- 211. 7a-[9-[(4,4,5,5,5,-Pentafluoropentyl)sulphinyl]nonyl]-estra-1,3,5(10)-triene-3,17b-diol
- [A synthetic estrogen receptor antagonist. Unlike tamoxifen (which has partial agonist effects) and the aromatase inhibitors (which reduce the estrogen available to tumor cells), fulvestrant binds competitively to estrogen receptors in breast cancer cells, resulting in estrogen receptor deformation and decreased estrogen binding. In vitro studies indicate that fulvestrant reversibly inhibits the growth of tamoxifen-resistant, estrogen-sensitive, human breast cancer cell lines. (NCI04) ( NCI )] (UMLS (NCI) C0935916) FULVESTRANT;
FULVESTRANT PREPARATION =Steroid; Pharmacologic Substance ;
=[AN500] ANTINEOPLASTIC HORMONES;
Unclassified Ingredients =FULVESTRANT 50 MG/ML;
| - 261. A-4828
- (UMLS (NCI) C0149248) =Organic Chemical; Pharmacologic Substance
|
- 212. 7alpha hydroxylase
- [nonEC. ( CSP )] (UMLS (CSP) C0599930) =Amino Acid, Peptide, or Protein; Enzyme =Oxygenase;
| - 262. A-65
- [An amide analogue of Trichostatin A studied for potential antineoplastic activity. A-65 inhibits zinc-dependent histone deacetylase, inducing terminal cell differentiation and anti-angiogenic activity. (NCI04) ( NCI )] (UMLS (NCI) C1510673) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 213. 8-Aminoisoindolo(1,2-b)quinazolin-12(10H)-one
- [A water insoluble heterocyclic amide with potential antineoplastic activity. Batracylin appears to intercalate into DNA and interferes with topoisomerase II activity, thereby inhibiting DNA replication and repair, and RNA and protein synthesis. The acetylated form of batracylin is highly toxic and capable of inducing unscheduled DNA synthesis. This agent should, therefore, only be administered in patients with a slow acetylator NAT-2 genotype. ( NCI )] (UMLS (NCI) C0053006) =Organic Chemical; Pharmacologic Substance
| - 263. A-85761
- (UMLS (NCI) C0384232) =Organic Chemical; Pharmacologic Substance ;
|
- 214. 8-Azaguanine
- [A purine analogue with potential antineoplastic activity. 8-Azaguanine interferes with the modification of transfer ribonucleic acid (tRNA) by competing with guanine for incorporation into tRNA catalyzed by the enzyme tRNA-guanine ribosyltransferase (tRNA-guanine transglycosylase). Altered guanine modification of tRNA has been implicated in cellular differentiation and neoplastic transformation. 8-Azaguanine also inhibits the formation of 43S and 80S initiation complexes, thereby interfering with initiation of translation and inhibiting protein synthesis. This agent inhibits tumor cell growth and stimulates cell differentiation. (NCI04) ( NCI )] (UMLS (NCI) C0004476) =Organic Chemical; Pharmacologic Substance
| - 264. A-DNA
- [A-DNA is a shorter and wider helix than B-DNA. Most RNA and RNA-DNA duplex are in this form. While deep, narrow major groove is not easily accessible to proteins but wide, shallow minor groove is accessible to proteins but with lower information content than major groove. A-DNA is the favored conformation at low water concentrations. Base pairs are tilted to helix axis and displaced from axis and sugar pucker is C3'-endo (in RNA 2'-OH inhibits C2'-endo conformation). When examined from the top of the helix, there is a large hole in the middle, the sugar phosphate backbone is at the edge of the helix, and the bases are displaced towards the edge. ( NCI )] (UMLS (NCI) C0000702) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance
|
- 215. 8a
- [Maxillary right central incisor abutment ( HL7V3.0 )] (UMLS (HL7) C1553640) =Medical Device =Artificial dentition;
| - 265. A-Esterase
- [Acts on many phenolic esters. The reactions of EC 3.1.8.1 aryldialkylphosphatase, were previously attributed to this enzyme. [EC 3.1.1.2 created 1961, modified 1989] (from IUBMB Enzyme Nomenclature). ( NCI )] (UMLS (NCI) C0052451) =Amino Acid, Peptide, or Protein; Enzyme
|
- 216. 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,2
- [novel immunosuppressive drug used in transplantation; may inhibit receptor mediated activation of mast cells. ( CSP )] (UMLS (NCI) C0072980) =Organic Chemical; Antibiotic =macrolide antibiotic;
[IM600] IMMUNE SUPPRESSANTS =SIROLIMUS 1 MG/ML;
SIROLIMUS 1 MG;
SIROLIMUS 2 MG | - 266. A-MethaPred
- (UMLS (NCI) C0701467) =Steroid; Pharmacologic Substance; Hormone
|
- 217. 9,10,Anthracenedicarboxaldehyde
- [An anthracenyl bishydrazone with antineoplastic activity. Bisantrene intercalates with and disrupts the configuration of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication. This agent is similar to doxorubicin in activity, but unlike doxorubicin, does not exhibit cardiotoxicity. (NCI04) ( NCI )] (UMLS (NCI) C0053776) =Organic Chemical; Pharmacologic Substance ;
| - 267. A-Microtubule
- (UMLS (NCI) C1510674) =Cell Component ;
|
- 218. 9,10-Anthracenedione
- [A polycyclic aromatic hydrocarbon derived from anthracene or pthalic anhydride. Anthraquinone is used in the manufacture of dyes, in the textile and pulp industries, and as a bird repellant. ( NCI )] (UMLS (NCI) C0050133) =Organic Chemical; Antibiotic
| - 268. A-myb Messenger RNA Overexpression
- (UMLS (NCI) C1510675) A-myb mRNA Overexpression;
=Cell or Molecular Dysfunction ;
|
- 219. 9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, Methyl Ester
- [A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow. This leads to a decrease in blood pressure. Eplerone is used in the treatment of hypertension and congestive heart failure. ( NCI )] (UMLS (NCI) C0961485) Eplerenone;
EPLERENONE PREPARATION;
=Steroid; Pharmacologic Substance =[CV704] POTASSIUM-SPARING/COMBINATIONS DIURETICS;
Unclassified Ingredients =EPLERENONE 25 MG;
EPLERENONE 50 MG;
EPLERENONE 100 MG;
| - 269. a-protein
- [HMGA1a is one of three protein products of the same gene, HMGA1, generated by alternative splicing. The HMGA1a protein contains three basic domains, named AT-hooks and an acidic C-terminal region. AT-hooks are responsible for binding to AT-rich sequences inside the minor groove of DNA. Phosphorylation of HMGA1a by both PKC and cdc-2 kinases strongly reduces its DNA binding affinity and is critical in cell cycle progression. HMGA1a activates the interferon-beta gene (IFN-beta) by functioning as the essential architectural component for the assembly and stability of the IFN-beta enhanceosome. (PMID11576996) ( NCI )] (UMLS (NCI) C0038164) =Amino Acid, Peptide, or Protein; Immunologic Factor; Indicator, Reagent, or Diagnostic Aid
|
- 220. 9-AC
- [An anticancer drug that belongs to the family of drugs called topoisomerase inhibitors. ( NCI )] (UMLS (NCI) C0214192) =Organic Chemical; Pharmacologic Substance ;
| - 270. A-RAF Protein Kinase
- [Encoded by human ARAF1 Gene (MIL/RAF Family), cytoplasmic A-RAF [serine/threonine] Protein Kinase contains a DAG binding and a RBD domain, and is involved in transduction of mitogenic signals from cell membrane to nucleus. ( NCI )] (UMLS (NCI) C0100762) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 221. 9-AC/G-CSF
- (UMLS (NCI) C0281574) =Therapeutic or Preventive Procedure
| - 271. A/He Mouse
- (UMLS (NCI) C1510706) =Mammal ;
|
- 222. 9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione
- [The acetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone acetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. ( NCI )] (UMLS (NCI) C0040866) =Steroid; Pharmacologic Substance ;
=(11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione;
[DE200] ANTI-INFLAMMATORY, TOPICAL;
[NT200] ANTI-INFLAMMATORIES, NASAL;
[OR900] DENTAL AND ORAL AGENTS, TOPICAL OTHER;
[RE101] ANTI-INFLAMMATORIES, INHALATION;
=(11beta,16alpha)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione;
TRIAMCINOLONE ACETONIDE PWDR;
TRIAMCINOLONE ACETONIDE 0.1 %;
TRIAMCINOLONE ACETONIDE 40 MG/ML;
TRIAMCINOLONE ACETONIDE 100 MCG/ACTUAT;
TRIAMCINOLONE ACETONIDE 10 MG/ML;
TRIAMCINOLONE ACETONIDE 55 MCG/ACTUAT;
TRIAMCINOLONE ACETONIDE 2.5 MG/GM;
TRIAMCINOLONE ACETONIDE 50 MCG/ACTUAT;
TRIAMCINOLONE ACETONIDE 3 MG/ML;
TRIAMCINOLONE ACETONIDE 3.3 MG/50GM;
TRIAMCINOLONE ACETONIDE 0.025 %;
TRIAMCINOLONE ACETONIDE 0.147 MG/GM;
TRIAMCINOLONE ACETONIDE 0.5 %;
TRIAMCINOLONE ACETONIDE 1 MG/GM | - 272. A/HeJ
- (UMLS (NCI) C1510705) A/HeJ Mouse;
=Mammal ;
|
- 223. 9-amino-20(S)-camptothecin
- (UMLS (NCI) C0950849) 9-Amino-20-(S)-camptothecin =Organic Chemical; Pharmacologic Substance
| - 273. A/J
- (UMLS (NCI) C1510707) A/J Mouse;
=Mammal ;
|
- 224. 9a
- [Maxillary left central incisor abutment ( HL7V3.0 )] (UMLS (HL7) C1553641) =Body Part, Organ, or Organ Component =Artificial dentition;
| - 274. A/JOlaHsd
- (UMLS (NCI) C1510708) A/JOlaHsd Mouse;
=Mammal ;
|
- 225. 9AC colloidal dispersion
- [A colloidal dispersion formulation of 9-Aminocamptothecin, a water-insoluble camptothecin derivative. Aminocamptothecin binds to the nuclear enzyme topoisomerase I, thereby inhibiting repair of single-strand DNA breakages. Because the terminal lactone ring of aminocamptothecin required for the agent's antitumor activity spontaneously opens under physiological conditions to an inactive carboxy form, the drug must be administered over an extended period of time to achieve effective cytotoxicity. ( NCI )] (UMLS (NCI) C0677807) =Organic Chemical; Pharmacologic Substance ;
| - 275. A/WySnJ
- (UMLS (NCI) C1510709) A/WySnJ Mouse;
=Mammal ;
|
- 226. A
- [Maxillary right second primary molar ( HL7V3.0 )] (UMLS (HL7) C0227089) =Body Part, Organ, or Organ Component =Primary dentition;
| - 276. A01, A04, A08, A13
- (UMLS (HL7) C1548674) =Intellectual Product =Message structure;
|
- 227. a
- [The period of time that it takes for Earth to make a complete revolution around the sun, approximately 365 days; a specific one year period. (NCI) ( NCI )] (UMLS (NCI) C0439234) =Temporal Concept =CalendarCycleTwoLetter;
CalendarCycleOneLetter;
UnitOfMeasureAtomInsens;
UnitOfMeasureAtomSens | - 277. A02
- (UMLS (HL7) C1548675) =Intellectual Product =Message structure;
|
- 228. A
- [One of the seven base units of the International System of Units (Systeme International d'Unites, SI), the unit of electric current, named after the French physicist Andre Ampere. It is that constant current which, if maintained in two straight parallel conductors of infinite length and zero diameter separated by one meter in a vacuum, would produce between these conductors a force equal to 2x10(e)7 newton per meter of length. This is dependent upon the definitions of the meter, kilogram, and second. One ampere represents 6.24 x 10(e+18) unit electric charge carriers, such as electrons, passing a specified fixed point in one second. ( NCI )] (UMLS (NCI) C0457243) =Quantitative Concept =UnitOfMeasureAtomInsens;
| - 278. A03
- (UMLS (HL7) C1548676) =Intellectual Product =Message structure;
|
- 229. A 2371
- [ ] (UMLS (CSP) C0702003) =Carbohydrate; Indicator, Reagent, or Diagnostic Aid; Antibiotic
| - 279. A05, A14, A28, A31
- (UMLS (HL7) C1548677) =Intellectual Product =Message structure;
|
- 230. A and D Ointment
- [A topical preparation containing fat-soluble vitamins A and D usually in a lanolin-petrolatum base, A and D Ointment promotes healing of minor burns, rashes, sunburn, skin irritations, and acne; and prevents diaper rash. Vitamin A is essential for diverse cellular functions, immune system functions, and maintenance of mucous membranes, while vitamin D regulates calcium and phosphorous metabolism. (NCI04) ( NCI )] (UMLS (NCI) C0305093) =Clinical Drug =[VT050] VITAMIN A;
[VT500] VITAMIN D | - 280. A06, A07
- (UMLS (HL7) C1548678) =Intellectual Product =Message structure;
|
- 231. A Disintegrin and Metalloprotease with Thrombospondin Motifs-1
- [A disintegrin and metalloproteinase with thrombospondin motifs-1 (ADAMTS-1), encoded by the ADAMTS1 gene is a member of the ADAMTS protein family. It cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors. It has anti-angiogenic activity and inhibits endothelial cell proliferation. ADAMTS1 may be associated with various inflammatory processes as well as development of cancer cachexia. It is likely to be necessary for normal growth, fertility, and organ morphology and function. ADAMTS1 is secreted and associated with the extracellular matrix. The Spacer Domain and the TSP Type-1 Domains are important for a tight interaction with the extracellular matrix. ADAMTS1 is expressed as a 110-kD protein, an 85-kD protein after cleavage at the subtilisin site, or as a 67-kD protein, which is most abundant, generated by an additional processing event. (From LocusLink, Swiss_Prot and NCI) ( NCI )] (UMLS (NCI) C1307941) A Disintegrin And Metalloproteinase With Thrombospondin Motifs 1;
ADAMTS1;
ADAM-TS1;
METH-1 =Amino Acid, Peptide, or Protein; Enzyme | - 281. A09, A10, A11, A12
- (UMLS (HL7) C1548679) =Intellectual Product =Message structure;
|
- 232. A Disintegrin and Metalloprotease with Thrombospondin Motifs-9
- [A disintegrin and metalloproteinase with thrombospondin motifs-9 (ADAMTS9), encoded by the ADAMTS9 gene, is a member of the ADAMTS protein family. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This enzyme contains four C-terminal TS motifs. The spacer domain and the TSP Type-1 domains are important for a tight interaction with the extracellular matrix. The precursor is cleaved by a furin endopeptidase. Two isoforms, a long form and a short form, may be produced by alternative splicing. ADAMTS9 is secreted and associated with the extracellular matrix. It is highly expressed in all fetal tissues and expressed slightly in adult ovary, pancreas, heart, kidney, lung, placenta, spinal cord and brain. (From LocusLink, Swiss_Prot and NCI) ( NCI )] (UMLS (NCI) C1257533) A Disintegrin and Metalloproteinase with Thrombospondin Motifs-9;
ADAMTS9;
ADAM-TS9 =Amino Acid, Peptide, or Protein; Enzyme ;
| - 282. A10/AS2-1
- (UMLS (NCI) C0281644) =Therapeutic or Preventive Procedure
|
- 233. A Disintegrin and Metalloproteinase Domain 11 Gene
- [This gene plays a role in cell-cell and cell-matrix interactions. ( NCI )] (UMLS (NCI) C1332015) ADAM11;
ADAM11 Gene;
=Gene or Genome ;
| - 283. A10/MTX
- (UMLS (NCI) C0796429) Antineoplaston A10/Methotrexate =Therapeutic or Preventive Procedure
|
- 234. A Disintegrin and Metalloproteinase Domain 11 Protein
- [This protein is a member of the ADAM protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. (LocusLink) ( NCI )] (UMLS (NCI) C1332016) ADAM11;
ADAM11 Protein;
Metalloproteinase-Like, Disintegrin-Like and Cysteine-Rich Protein =Amino Acid, Peptide, or Protein; Biologically Active Substance | - 284. A15
- (UMLS (HL7) C1548680) =Intellectual Product =Message structure;
|
- 235. A Disintegrin and Metalloproteinase Domain 15
- [MDC-15; ADAM-15; metargidin. Member of a sequence-related family of cysteine-rich membrane proteins containing metalloproteinase-like and disintegrin-like domains; contains an RGD sequence in its disintegrin domain. ( NCI )] (UMLS (NCI) C1313290) ADAM15;
EC 3.4.24.-;
MDC15;
Metalloprotease-RGD-Disintegrin Protein;
Metalloproteinase-Like Disintegrin-Like and Cysteine-Rich Protein 15;
Metargidin =Amino Acid, Peptide, or Protein; Enzyme ;
| - 285. A16
- (UMLS (HL7) C1548681) =Intellectual Product =Message structure;
|
- 236. A Disintegrin and Metalloproteinase Domain 15 Gene
- [This gene is involved in the restructuring of the mesangial matrix. ( NCI )] (UMLS (NCI) C1332017) ADAM15;
ADAM15 Gene;
=Gene or Genome ;
| - 286. A17
- (UMLS (HL7) C1548682) =Intellectual Product =Message structure;
|
- 237. A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, Alpha, Converting Enzyme) Gene
- [This gene plays a role in the cleavage of membrane proteins, resulting in the release of their extracellular domains from cells. ( NCI )] (UMLS (NCI) C1412186) ADAM17;
ADAM17 Gene =Gene or Genome ;
| - 287. A18
- (UMLS (HL7) C1548683) =Intellectual Product =Message structure;
|
- 238. A Disintegrin-Like and Metalloprotease (Reprolysin Type) with Thrombospondin Type 1 Motif, 1 Gene
- [This gene is involved in the inhibition of angiogenesis and cell proliferation. ( NCI )] (UMLS (NCI) C1332018) ADAMTS1;
ADAMTS1 Gene;
=Gene or Genome ;
| - 288. A19
- (UMLS (HL7) C1549870) =Intellectual Product =Message structure;
|
- 239. A Disintegrin-Like and Metalloprotease (Reprolysin Type) with Thrombospondin Type 1 Motif, 9 Gene
- [This gene plays a role in apoptosis and development. ( NCI )] (UMLS (NCI) C1332020) ADAMTS9;
ADAMTS9 Gene;
=Gene or Genome ;
| - 289. A1G4 anti-idiotype monoclonal antibody vaccine
- [An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id A1G4 MoAb may elicit cellular and humoral immune responses against GD2 expression tumor cells. ( NCI )] (UMLS (NCI) C0677670) =Pharmacologic Substance; Immunologic Factor ;
|
- 240. A follow up visit from a previous appointment
- (UMLS (HL7) C1548402) =Idea or Concept =Appointment reason codes;
| - 290. A20
- (UMLS (HL7) C1548684) =Intellectual Product =Message structure;
|
- 241. A generic substitution was dispensed.
- (UMLS (HL7) C1549557) =Idea or Concept =Substitution Status;
| - 291. A21, A22, A23, A25, A26, A27, A29, A32, A33
- (UMLS (HL7) C1548685) =Intellectual Product =Message structure;
|
- 242. A Kinase (PRKA) Anchor Protein (Gravin) 12 Gene
- [This gene plays a role in signal transduction and angiogenesis. ( NCI )] (UMLS (NCI) C1332070) AKAP12;
AKAP12 Gene;
=Gene or Genome | - 292. A24
- (UMLS (HL7) C1548686) =Intellectual Product =Message structure;
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- 243. A Kinase (PRKA) Anchor Protein (Yotiao) 9
- [The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in many isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. (from LocusLink) ( NCI )] (UMLS (NCI) C0672770) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 293. A27.15
- [A murine IgG1 monoclonal antibody directed against the human transferrin (Tf) receptor. Monoclonal antibody A27.15 binds to the Tf receptor, blocking the binding of transferrin to the receptor and resulting in decreased tumor cell growth. (NCI04) ( NCI )] (UMLS (NCI) C0677772) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
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- 244. A Kinase (PRKA) Anchor Protein (Yotiao) 9 Gene
- [This gene plays a role in signal transduction and modulates synaptic transmission. ( NCI )] (UMLS (NCI) C1332072) AKAP9;
AKAP9 Gene;
=Gene or Genome | - 294. A28807, Rat Strain
- [Very docile. Susceptible to the induction of autoimmune thyroiditis. Low and intermediate antibody responses to 1 and 10 g BSA, respectively. Low antibody response to streptococcal group A carbohydrate; not linked to the MHC. High relative heart weight in 10-week old males (20/23). ( NCI )] (UMLS (NCI) C1510676) =Mammal ;
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- 245. A Kinase (PRKA) Anchor Protein 12
- [The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. (from LocusLink) ( NCI )] (UMLS (NCI) C0289793) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 295. A2G Mouse
- (UMLS (NCI) C1510677) =Mammal ;
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- 246. A Kinase (PRKA) Anchor Protein 13 Gene
- [This gene is involved in signal transduction and protein trafficking. ( NCI )] (UMLS (NCI) C1332071) AKAP13;
AKAP13 Gene;
=Gene or Genome | - 296. A30, A34, A35, A36, A46, A47, A48, A49
- (UMLS (HL7) C1548687) =Intellectual Product =Message structure;
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- 247. A Kinase Anchor Protein 13
- [Encoded by human oncogene AKAP13 Gene, 424-amino acid 49 kD A Kinase Anchor Protein 13 is a signal transduction RHO/RAC GEF involved in cytoskeletal organization and cell cycle progression. Alpha helical hydrophilic LBC is conserved among vertebrates and expressed in skeletal muscle, heart, lung, and hematopoietic cells. It contains phosphorylation sites, N-terminal DH and PH domains, and an N-terminal EF-hand motif. LBC binds to PKA RII tethering it near substrates. AKAP13 stimulates RHO/RAC, but not CDC42 or RAS. In ovary, placenta, breast, and testis, 170 kD BRX contains a LBC region preceded by 3 novel regions; C-terminal regions 4 and 5 bind to the ESR1 ligand-binding domain. BRX also binds RXR, PPAR, and THR. Chimeric onco-LBC lacks the C-terminus, which promotes transforming activity. Proto-LBC is membrane bound; onco-LBC is cytosolic. (OMIM, Swiss-Prot, and NCI) ( NCI )] (UMLS (NCI) C1318045) AKAP13;
A-Kinase (PRKA) Anchor Protein 13;
BRX;
HT31;
LBC;
P47 =Amino Acid, Peptide, or Protein; Biologically Active Substance | - 297. A32
- [Active in neural crest cells during development and expressed primarily in neuroectodermal lineages and vascular smooth muscle in adult tissues by human MCAM Gene (Ig Superfamily), 646-aa 72-kDa (precursor) Melanoma Adhesion Molecule is a cell surface type I membrane glycoprotein containing 3 Ig-like C2-type domains and 2 Ig-like V-type domains and a possible adhesion molecule homologue of cell adhesion molecule NCAM. (NCI) ( NCI )] (UMLS (NCI) C0386212) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
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- 248. A kinase anchoring protein
- [class of proteins that target cAMP dependent protein kinase to various sites within the cell. ( CSP )] (UMLS (CSP) C0872014) AKAP;
=Amino Acid, Peptide, or Protein; Biologically Active Substance =binding protein;
| - 298. A33
- [A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells. ( NCI )] (UMLS (NCI) C0392959) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
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- 249. A previously unscheduled walk-in visit
- (UMLS (HL7) C1548404) =Intellectual Product =Appointment reason codes;
| - 299. A37
- (UMLS (HL7) C1548688) =Intellectual Product =Message structure;
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- 250. A product from a controlled/non-related inventory was evaluated
- (UMLS (HL7) C1546983) =Idea or Concept =Product source;
| - 300. A38
- (UMLS (HL7) C1548689) =Intellectual Product =Message structure;
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