- 1. ANK Domain
- [Ankyrin Repeats are tandem modules of about 33 amino acids. The conserved domain structure has been described as side-by-side anti-parallel alpha helices connected by intervening beta hairpin motifs or as beta, alpha, alpha, beta secondary structures or as an L-shaped beta-hairpin and two alpha-helices. The repeats associate to form a higher order structure. Despite sequence variation, the domain core maintains a stable surface of contact residues to mediate protein-protein interactions. Target protein binding involves contacts by the beta hairpin tips and the helical bundle surface facing the Ankyrin groove. ANK repeats have been identified in over 1700 functionally diverse proteins, primarily from eukaryotes; no common theme among the protein targets has been identified. The Ankyrin cytoskeletal protein is composed almost entirely of these repeats. ( NCI )] (UMLS (NCI) C0162527) =Molecular Function
| - 20. Ankylosing spondylitis and other inflammatory spondylopathies
- (UMLS (ICD9CM) C0003089) =Disease or Syndrome ;
|
- 2. ankle
- [joint formed by the articulation of the lower leg bones with the talus; ankle connects the foot with the leg. ( CSP )] (UMLS (CSP) C0003086) =Body Location or Region ;
| - 21. ankylosis
- [Fixation and immobility of a joint. ( MSH )] (UMLS (CSP) C0003090) =Acquired Abnormality; Disease or Syndrome
|
- 3. Ankle amputation status
- [ ] (UMLS (ICD9CM) C1955596) STATUS AMPUT ANKLE;
=Finding | - 22. ankylosis (surgical)
- [surgical immobilization of a joint by fusion of joint surfaces by promoting proliferation of bone cells; joint fusion. ( CSP )] (UMLS (CSP) C0003881) =Therapeutic or Preventive Procedure ;
|
- 4. ANKLE ARTHROSCOPY
- [ ] (UMLS (ICD9CM) C0188624) =Diagnostic Procedure
| - 23. ANKYLOSIS EAR OSSICL NEC
- (UMLS (ICD9CM) C0155486) =Disease or Syndrome ;
|
- 5. ANKLE ENTHESOPATHY NEC
- (UMLS (ICD9CM) C0158323) =Disease or Syndrome
| - 24. ANKYLOSIS MALLEUS
- [ ] (UMLS (ICD9CM) C0584793) =Finding
|
- 6. ANKLE ENTHESOPATHY NOS
- (UMLS (ICD9CM) C0158319) =Disease or Syndrome
| - 25. Ankylosis of ankle and foot joint
- [ ] (UMLS (ICD9CM) C1963544) ANKYLOSIS-ANKLE;
=Acquired Abnormality; Disease or Syndrome |
- 7. Ankle Fracture
- (UMLS (NCI) C0159877) =Injury or Poisoning
| - 26. Ankylosis of forearm joint
- [ ] (UMLS (ICD9CM) C0158121) =Acquired Abnormality; Disease or Syndrome
|
- 8. ANKLE FUSION
- [ ] (UMLS (ICD9CM) C0188661) =Therapeutic or Preventive Procedure
| - 27. Ankylosis of hand joint
- [ ] (UMLS (ICD9CM) C0158122) =Acquired Abnormality; Disease or Syndrome
|
- 9. Ankle Joint
- [The joint that is formed by the inferior articular and malleolar articular surfaces of the TIBIA; the malleolar articular surface of the FIBULA; and the medial malleolar, lateral malleolar, and superior surfaces of the TALUS. ( MSH )] (UMLS (NCI) C0003087) =Body Space or Junction ;
| - 28. Ankylosis of joint of multiple sites
- [ ] (UMLS (ICD9CM) C0158127) =Acquired Abnormality; Disease or Syndrome
|
- 10. ANKLE JOINT BIOPSY
- [ ] (UMLS (ICD9CM) C0188496) =Diagnostic Procedure
| - 29. Ankylosis of joint of other specified sites
- [ ] (UMLS (ICD9CM) C0158126) =Disease or Syndrome ;
|
- 11. Ankle joint replaced by other means
- [ ] (UMLS (ICD9CM) C0375842) =Finding
| - 30. Ankylosis of joint of pelvic region and thigh
- [ ] (UMLS (ICD9CM) C0158123) =Acquired Abnormality; Disease or Syndrome
|
- 12. Ankle Lateral Collateral Ligament
- (UMLS (NCI) C0225187) =Body Part, Organ, or Organ Component
| - 31. Ankylosis of joint of shoulder region
- [ ] (UMLS (ICD9CM) C0158119) =Acquired Abnormality; Disease or Syndrome
|
- 13. Ankle Skin
- (UMLS (NCI) C0222286) =Body Part, Organ, or Organ Component
| - 32. Ankylosis of lower leg joint
- [ ] (UMLS (ICD9CM) C0158124) =Acquired Abnormality; Disease or Syndrome
|
- 14. Ankle sprain
- [ ] (UMLS (ICD9CM) C0160087) =Injury or Poisoning
| - 33. ANKYLOSIS OF TEETH
- [Solid fixation of a tooth resulting from fusion of the cementum and alveolar bone, with obliteration of the periodontal ligament. It is uncommon in the deciduous dentition and very rare in permanent teeth. (Jablonski's Dictionary of Dentistry, 1992) ( MSH )] (UMLS (ICD9CM) C0155930) =Disease or Syndrome ;
=Dental Disorder; |
- 15. ANKLE STRUCTURE DIVISION
- [ ] (UMLS (ICD9CM) C0177514) =Therapeutic or Preventive Procedure
| - 34. Ankylosis of upper arm joint
- [ ] (UMLS (ICD9CM) C0158120) =Acquired Abnormality; Disease or Syndrome
|
- 16. Ankle symptoms/complaints
- (UMLS (ICPC) C0497270) (Ankle symptoms/complaints; S./K. ORKATILA; Sympt/klage fra fodled; Enkel symptomen/klachten; NILKAN OIREET/VAIVAT; Sympt plaintes cheville; Symptome/Beschwerden Knoechel; tlunot o simpt'- karsul; boka tunet/panasz; Sintomi/disturbi caviglia; ANKEL SYMPT/PLAGER; Sinais/sintomas do tornozelo; S/s del tobillo; SYMPTOM/KLAGOMAL BETR VRIST) =Sign or Symptom =musculoskeletal; Symptoms and Complaints Component
| - 35. ankyrin
- [loosely associated membrane protein which links spectrin to integral membrane proteins such as "band 3." ( CSP )] (UMLS (CSP) C0051926) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=cytoskeletal protein; |
- 17. ANKLE SYNOVECTOMY
- [ ] (UMLS (ICD9CM) C0188497) =Therapeutic or Preventive Procedure
| - 36. Ankyrin Repeat Domain 30A
- [Encoded by human Breast Cancer Antigen NY-BR-1 Gene expressed in breast and testis, the 1341-amino acid 152 kD NY-BR-1 Protein contains an apparent DNA-binding bZIP motif and five tandem ankyrin repeats, implying a transcription factor involved in protein-protein interactions. (from Cancer Res 2001; 61:2055, SWISS-PROT, LocusLink, and NCI) ( NCI )] (UMLS (NCI) C1332617) Breast Cancer Antigen NY-BR-1;
NY-BR-1; =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 18. ANKYL VERT HYPEROSTOSIS
- [A disease of elderly men characterized by large osteophytes that bridge vertebrae and ossification of ligaments and tendon insertions. ( MSH )] (UMLS (ICD9CM) C0020498) =Disease or Syndrome =Bone Hypertrophy;
Spinal Osteophytosis | - 37. Ankyrin Repeat-Containing Protein KRIT1
- [Ankyrin Repeat-Containing Protein KRIT1, encoded by the CCM1 gene, interacts with ICAP-1 and may be involved in bidirectional signaling between integrin molecules and the cytoskeleton. KRIT1 may help determine endothelial cell shape and function in response to cell-cell and cell-matrix interactions by guiding cytoskeletal structure. Defects in the CCM1 gene are responsible for the development of cerebral cavernous malformations, a relatively rare disease causing vascular malformations that may involve any part of the central nervous system. KRIT1 may affect cell adhesion processes via integrin signaling in CCM1 pathogenesis. KRIT1 also interacts with RAP1A (a member of the Ras family of GTPases) and may be involved in the RAP1A signal transduction pathway in vasculogenesis or angiogenesis. KRIT1 contains 4 ankyrin repeats, 1 band 4.1-like domain, and 1 FERM domain. (From NCI) ( NCI )] (UMLS (NCI) C1366911) CAM;
CCM1; Cerebral Cavernous Malformations 1; Krev Interaction Trapped 1; KRIT1 =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 19. ankylosing spondylitis
- [Inflammatory joint disease affecting the spine. It occurs predominantly in young males and produces pain and stiffness as a result of inflammation of the sacroiliac, intervertebral, and costovertebral joints. Etiology is unknown. ( MSH )] (UMLS (CSP) C0038013) =Disease or Syndrome ;
=ankylosis; Arthritis, Rheumatoid; INFLAM SPONDYLOPATHY NOS; | |