[Glioma-Amplified Sequence-41, encoded by the human GAS41 gene, may be a transcription factor and common binding factor for the TACC family proteins. An increased copy number of this gene is found in glioblastoma multiforme and astrocytoma III, and at a high frequency in astrocytoma grades I and II. The GAS41 gene is the first gene found with increased copy number in low-grade glioma, which provides the first evidence that gene amplification can occur in early tumor development. (From OMIM and NCI) ( NCI )]
UMLS (NCI) C0668673 - Amino Acid, Peptide, or Protein
- Biologically Active Substance
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