- 1. GADD45 Gene Product
- [Growth Arrest and DNA-Damage-Inducible, Alpha, encoded by the GADD45A gene, is widely expressed in normal tissues and its expression is increased by DNA damage. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. The GADD45A protein responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. This nuclear protein interacts with the proliferating cell nuclear antigen (PCNA), a component of DNA replication/repair complexes, and the cyclin dependent kinase inhibitor p21Cip1. ( NCI )] (UMLS (NCI) C1098917) GADD45A;
GADD45A Protein;
Growth Arrest and DNA Damage-Inducible Gene 45 Protein;
Growth Arrest and DNA-Damage-Inducible, Alpha =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 5. Gadolinium Texaphyrin
- [A substance that makes tumor cells more sensitive to radiation; it can also enhance tumor images using magnetic resonance imaging (MRI). Motexafin gadolinium belongs to the family of drugs called metalloporphyrin complexes. Also called gadolinium texaphyrin. ( NCI )] (UMLS (NCI) C0964264) Gd (III) Texaphryin;
Gd-Tex;
Motexafin Gadolinium =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid |
- 2. GADD45A
- [This gene plays a role in signal transduction and is induced in response to environmental stress. It is involved in apoptosis, DNA repair and negative regulation of cell growth. ( NCI )] (UMLS (NCI) C1333655) GADD45A Gene;
Growth Arrest and DNA-Damage-Inducible, Alpha Gene;
=Gene or Genome ;
| - 6. GADOTERIDOL
- (UMLS (NCI) C0060930) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
=Heterocyclic Compound;
Organometallic Compound;
[DX900] DIAGNOSTICS, OTHER;
=GADOTERIDOL 279.3 MG/ML;
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- 3. GADODIAMIDE
- (UMLS (NCI) C0082646) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
=Gadolinium DTPA;
Inactive Ingredient Preparations =GADODIAMIDE 287 MG/ML;
| - 7. Gadoversetamide
- [A paramagnetic extracellular magnetic resonance imaging (MRI) contrast agent that facilitates visualization of abnormal vascularity. When placed in a magnetic field, gadoversetamide decreases T1 (spin-lattice or longitudinal relaxation time) and T2 (spin-spin or transverse relaxation time) values in tissues where it accumulates. At the recommended dose, the effect is primarily on T1 relaxation time, and produces an increase in signal intensity. Gadoversetamide does not cross the intact blood-brain barrier. However, abnormal vascularity or disruption of the blood-brain barrier allows accumulation of gadoversetamide. (NCI05) ( NCI )] (UMLS (NCI) C0754820) GADOVERSETAMIDE PREPARATION =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
=Optimark;
[DX201] IMAGING AGENTS (IN VIVO) RADIOPHARMACEUTICALS =GADOVERSETAMIDE 330.9 MG/ML;
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- 4. gadolinium
- [element of the rare earth family of metals, atomic symbol Gd, atomic number 64, and atomic weight 157.25; chelated gadolinium is used as a paramagnetic contrast agent in magnetic resonance imaging, and Gd153 is used in dual photon absorptiometry. ( CSP )] (UMLS (CSP) C0016911) =Pharmacologic Substance; Element, Ion, or Isotope =Metals, Rare Earth;
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