[A murine IgM monoclonal antibody (MoAb) developed for the potential treatment of graft versus host disease (GvHD). MoAb ABX-CBL recognizes human CD147 antigen, weakly expressed on human leukocytes and up-regulated on activated lymphocytes. This MoAb is capable of neutralizing inflammatory reactions via a complement-dependent cytotoxic mechanism. However, MoAb ABX-CBL does not offer an improvement over antithymocyte globulin in the treatment of acute steroid resistant GVHD. ( NCI )] (UMLS (NCI) C0935795) Monoclonal Antibody ABX-CBL; =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor