[Forkhead Box O3A, encoded by the FOXO3A Gene, belongs to the forkhead family of transcription factors characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. (From LocusLink and NCI) ( NCI )]
UMLS (NCI) C1333633FOXO3A
- Amino Acid, Peptide, or Protein
- Biologically Active Substance