- 1. Fc domain
- [ ] (UMLS (CSP) C0872168) =Amino Acid Sequence ;
| - 7. Fc receptor augmenting factor
- [ ] (UMLS (CSP) C0598793) =Amino Acid, Peptide, or Protein; Immunologic Factor
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- 2. Fc Fragment
- [Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN. ( MSH )] (UMLS (NCI) C0021032) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
| - 8. FC-1157a
- (UMLS (NCI) C0700082) =Organic Chemical; Pharmacologic Substance
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- 3. Fc Fragment of IgG, Low Affinity IIA, Receptor (CD32) Gene
- [This gene is involved in the regulation of host immune responses and phagocytosis. ( NCI )] (UMLS (NCI) C1414553) FCGR2A;
FCGR2A Gene =Gene or Genome | - 9. Fc-Gamma Receptor II
- [Generally expressed in monocytes, macrophages, polymorphonuclear cells, NK cells, T- and B-lymphocytes, and platelets, Fc-Gamma Receptors II are type I cell surface membrane protein low affinity receptors for aggregated IgG Fc region with 2 extracellular IgC2 domains and cytoplasmic ITIM or ITAM motifs involved in cell activation upon receptor aggregation. IgG binding initiates essential effector and regulatory cellular responses against foreign pathogens and soluble antigens that induce phagocytosis of antigen-antibody complexes, removing them from circulation, and modulate B-cell antibody production. (NCI) ( NCI )] (UMLS (NCI) C0796385) =Amino Acid, Peptide, or Protein; Receptor
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- 4. Fc Fragment of IgG, Low Affinity IIB, Receptor (CD32) Gene
- [This gene plays a role in the inhibition of immune functions and cellular proliferation. ( NCI )] (UMLS (NCI) C1414554) FCGR2B;
FCGR2B Gene =Gene or Genome | - 10. FCE 21336
- (UMLS (NCI) C0701142) =Organic Chemical; Pharmacologic Substance ;
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- 5. Fc Fragment of IgG, Low Affinity IIIA, Receptor (CD16A) Gene
- [This gene plays a role in the mediation of antibody-dependent cytotoxicity and phagocytosis. ( NCI )] (UMLS (NCI) C1414555) FCGR3A;
FCGR3A Gene =Gene or Genome | - 11. FCE 24517
- (UMLS (NCI) C0082557) =Organic Chemical; Pharmacologic Substance ;
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- 6. Fc Fragment of IgG, Low Affinity IIIB, Receptor (CD16B) Gene
- [This gene is involved in the regulation of immune responses and ligand-binding interactions. ( NCI )] (UMLS (NCI) C1414556) FCGR3B;
FCGR3B Gene =Gene or Genome | - 12. Fce 26644
- (UMLS (NCI) C0251622) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
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