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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
F F F- F0 FA FB FC FD FE FF FG FH FI FJ FK FL FM FN FO FP FR FS FT FU FX FY
FG FGF FGR FGS

FGFR Substrate 3

[Encoded by human FRS3 Gene, 492-aa 54-kDa plasma membrane-associated FGFR Substrate 3 is an FGFR substrate that links FGFR stimulation to RAS activators. Similar (49% identical) to FRS2, FRS3 also contains a myristylation sequence, a PTB domain, and Tyr-containing motifs that govern GRB2 and SHP2 recruitment. FRS2 and FRS3 bind directly to FGFR1; an FGFR1 juxtamembrane segment and the PTB domain appear to interact and mediate FRS Tyr phosphorylation. (NCI) ( NCI )]
UMLS (NCI) C1333545
Fibroblast Growth Factor Receptor Substrate 3
FRS2B
FRS2-Beta
FRS3
SNT2
SUC1-Associated Neurotrophic Factor Target 2
 
Amino Acid, Peptide, or Protein
Biologically Active Substance
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