FES

[Human Oncogene FPS-FES is a mutated variant of FES Gene (FES/FPS Subfamily), which encodes 822 aa 93-kDa Tyrosine-Protein Kinase FES/FPS, a tyrosine-specific protein kinase involved in normal hematopoiesis and containing an FCH and SH2 domain. The FES chromosomal location is linked to a translocation identified in patients with acute promyelocytic leukemia. A truncated transcript is generated utilizing a start site in a far downstream exon. Oncogene FPS-FES disrupts normal cell function. ( NCI )]

UMLS (NCI) C0812383

FPS
Fujinami Sarcoma Virus and Feline Sarcoma Virus Transforming Gene
Oncogene FES
Oncogene FPS-FES