[Leukotriene B4 Receptor, encoded by the LTB4R gene, belongs to family 1 of G-protein coupled receptors. This protein is a receptor for extracellular ATP, UTP and ADP, and its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. This protein may be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. It is also a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. It is expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver, with high level of expression in lymphoid tissues. (from Swiss-Prot) ( NCI )]
UMLS (NCI) C1307920Chemokine Receptor-Like 1
G Protein-Coupled Receptor 16
Leukotriene B4 Receptor
LTB4R
P2Y Purinoceptor 7
- Amino Acid, Peptide, or Protein
- Receptor