- 1. CHK
- [Expressed in various myeloid cells, brain, and lung by human MATK Gene (CSK Family), 507-aa 56-kDa cytoplasmic Megakaryocyte-Associated Tyrosine Kinase is similar to CSK tyrosine kinase. MATK contains an SH2 and SH3 domain, a catalytic domain, and a unique N-terminus; it lacks myristylation signals, a negative regulatory phosphorylation site, and an autophosphorylation site. Able to phosphorylate and inactivate SRC tyrosine kinases, MATK may regulate SRC activity in brain by phosphorylating the C-terminal negative regulatory tyrosine. Likely to play a significant role in signal transduction in hematopoietic cells, MATK may inhibit T-cell proliferation. (NCI) ( NCI )] (UMLS (NCI) C0250935) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 2. CHKA
- [This gene is involved in the biosynthesis of phosphatidylcholine. ( NCI )] (UMLS (NCI) C1332757) CHKA Gene;
Choline Kinase Alpha Gene =Gene or Genome ; |