- 6201. Alpha Therapeutic Corporation
- [Alpha Therapeutic Corporation ( HL7V3.0 )] (UMLS (HL7) C1546860) =Health Care Related Organization =Manufacturers of Vaccines (code=MVX);
VaccineManufacturer | - 6251. Alteration of consciousness
- [ ] (UMLS (ICD9CM) C0234428) =Sign or Symptom
|
- 6202. alpha(sup 6)-((tert-Butylamino)methyl)-3-hydroxy-2,6-pyridinedimethanol Monoacetate(salt)
- [The acetate salt form of pirbuterol, a synthetic catecholamine and a pyridine derivative with sympathomimetic and bronchodilatory effects. Pirbuterol acetate selectively stimulates beta-2 adrenergic receptors, resulting in initiation of intracellular adenylate cyclase activity leading to increased levels of cAMP. As a result muscle relaxation (broncho- and vasodilation) occurs via cAMP-dependent signal transduction. In addition, elevated levels of cAMP inhibit release of inflammatory mediators from mast cells. ( NCI )] (UMLS (NCI) C0724666) Pirbuterol Acetate;
PIRBUTEROL ACETATE PREPARATION =Organic Chemical; Pharmacologic Substance ;
=PIRBUTEROL;
=PIRBUTEROL ACETATE 0.2 MG/ACTUAT | - 6252. ALTERATION OF SENSATIONS
- (UMLS (ICD9CM) C1135206) Alterations of sensations =Disease or Syndrome
|
- 6203. alpha,alpha,alpha,alpha',alpha',alpha'-Hexafluoro-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxy-2',5'-xylidide
- [A synthetic 4-azasteroid compound. Dutasteride competitively and specifically binds to isoenzymes 1 and 2 of 5 alpha-reductase, forming stable enzyme complexes and inhibiting the conversion of testosterone to 5 alpha-dihydrotestosterone (DHT); the reduction in DHT activity may mitigate or prevent enlargement of the prostate gland. The type 2 5 alpha-reductase isoenzyme is primarily active in the reproductive tissues, while the type 1 isoenzyme is also active in skin and the liver. ( NCI )] (UMLS (NCI) C0754659) Avolve,(5alpha,17beta)-N-(2,5-Bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide;
DUTASTERIDE;
DUTASTERIDE UNIDENTIFIED;
DUTASTERIDE PREPARATION;
DUTASTERIDE UNIDENTIFIED =Organic Chemical; Pharmacologic Substance ;
=[HS900] HORMONES/SYNTHETICS/MODIFIERS, OTHER;
Unclassified Ingredients =DUTASTERIDE 0.5 MG;
| - 6253. Alterations in Hearing
- (UMLS (NCI) C0429199) =Finding
|
- 6204. alpha-(1-[tert-Butylamino]ethyl)-2,5-dimethoxybenzyl Alcohol Hydrochloride
- [The hydrochloride salt form of butoxamine, a selective beta-2 adrenergic antagonist. Butoxamine is used primarily in animal and tissue experiments to identify beta-2 receptors and their function. ( NCI )] (UMLS (NCI) C0282081) =Organic Chemical; Pharmacologic Substance ;
| - 6254. Alterations in Smell or Taste
- (UMLS (NCI) C1332239) =Sign or Symptom ;
|
- 6205. alpha-(2,4-difluorophenyl)-alpha- (1,2,4-triazol-1-ylmethyl)-1,2, 4- triazole-1-ethanol
- [alpha-(2,4-difluorophenyl)-alpha- (1,2,4-triazol-1-ylmethyl)-1,2, 4- triazole-1-ethanol; an antifungal with potential efficacy for patients unable to take amphotericin B or who are immunologically compromised, as in AIDS. ( CSP )] (UMLS (NCI) C0016277) =Organic Chemical; Pharmacologic Substance ;
=[AM700] ANTIFUNGALS;
Triazoles =FLUCONAZOLE 100 MG;
FLUCONAZOLE 150 MG;
FLUCONAZOLE 2 MG/ML;
FLUCONAZOLE 200 MG;
FLUCONAZOLE 50 MG;
FLUCONAZOLE 10 MG/ML;
FLUCONAZOLE 40 MG/ML | - 6255. ALTERED MENTAL STATUS
- (UMLS (ICD9CM) C0278061) =Mental or Behavioral Dysfunction
|
- 6206. alpha-(2-chloro-4-(4,6-diamino-2,2-dimethyl-s-trizin-1(2H)-yl)phenoxy)-N,N-dimethyl-m-toluamide ethanesulfonic acid
- [A synthetic dihydrotriazine derivative with antineoplastic properties. As an antifolate agent related to methotrexate (MTX), triazinate inhibits the enzyme dihydrofolate reductase (DHFR), resulting in decreased tetrahydrofolate production and interference with thymidylate synthesis. Unlike MTX, this agent is not converted to polyglutamate forms. Triazinate also inhibits the transport of folates and may be selectively toxic to MTX-resistant tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C0077008) =Organic Chemical; Pharmacologic Substance ;
| - 6256. Alternaria
- [A mitosporic Loculoascomycetes fungal genus including several plant pathogens and at least one species which produces a highly phytotoxic antibiotic. Its teleomorph is Lewia. ( MSH )] (UMLS (CSP) C0002343) =Fungus
|
- 6207. alpha-1,3,5-triglycidyl-s-triazinetrione
- [A triazene triepoxide with antineoplastic activity. Teroxine alkylates and cross-links DNA, thereby inhibiting DNA replication. (NCI04) ( NCI )] (UMLS (NCI) C0043891) =Organic Chemical; Pharmacologic Substance ;
| - 6257. alternate
- [Designates substitute versions for the document in which the link occurs. When used together with the lang attribute, it implies a translated version of the document. When used together with the media attribute, it implies a version designed for a different medium (or media). ( HL7V3.0 )] (UMLS (HL7) C1552848) =Idea or Concept =HtmlLinkType;
|
- 6208. Alpha-1,4-N-acetylhexosaminyltransferase EXTL2
- [Ubiquitously expressed by human EXTL2 Gene (EXT Family), 330-aa 37.5-kDa Exostosin-Like 2 is a type II membrane protein glycosyltransferase of the endoplasmic reticulum that initiates heparan sulfate/heparin biosynthesis by alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate and heparin chains. A soluble EXTL2 form, derived from proteolytic processing of the membrane form, is found in serum. (NCI) ( NCI )] (UMLS (NCI) C1308415) Alpha-GalNAcT EXTL2;
Exostosin-Like 2 Protein;
EXTL2;
EXT-Related Protein 2;
=Amino Acid, Peptide, or Protein; Enzyme | - 6258. Alternate character set handling scheme
- (UMLS (HL7) C1547750) =Idea or Concept =HL7 Vocabulary Version 2.5;
=This is the default, indicating that there is no character set switching occurring in this message.;
"The character set switching mode specified in HL7 2.5, section 2.7.2, _Escape sequences supporting multiple character sets_ and section 2.A.46, ""XPN _ extended person name""."
;"This standard is titled ""Information Technology - Character Code Structure and Extension Technique"". ." |
- 6209. Alpha-Beta-Omega Interferon Receptor-1
- [Encoded by human IFNAR1 Gene (Type II Cytokine Receptor Family), 557-aa 64-kDa (precursor) ubiquitous type I membrane protein Interferon Alpha-Beta Receptor Alpha Chain contains 3 fibronectin type III domains and is the alpha subunit of Interferon Alpha Receptor Complex, a heteromeric receptor for type I IFNs, alpha and beta, composed of at least 2 chains, IFNAR1 (alpha chain) and IFNAR2 (beta chain). In mediating innate immune responses to viral infection and specific interferon inhibition of virus replication, binding of alpha and beta IFNs triggers tyrosine phosphorylation of JAKs, TYK2, STAT proteins, autophosphorylation, and tyrosine phosphorylation by TYK2. (NCI) ( NCI )] (UMLS (NCI) C0380190) =Amino Acid, Peptide, or Protein; Receptor
| - 6259. Alternate character sets
- (UMLS (HL7) C1547621) =Intellectual Product =HL7 Vocabulary Version 2.5;
=The printable characters from the ISO 8859/1 Character set;
The printable characters from the ISO 8859/2 Character set;
The printable characters from the ISO 8859/3 Character set;
The printable characters from the ISO 8859/4 Character set;
The printable characters from the ISO 8859/5 Character set;
The printable characters from the ISO 8859/6 Character set;
The printable characters from the ISO 8859/7 Character set;
The printable characters from the ISO 8859/8 Character set;
The printable characters from the ISO 8859/9 Character set;
The printable 7-bit ASCII character set.;
Code for Taiwanese Character Set (BIG-5);
Code for Taiwanese Character Set (CNS 11643-1992);
Code for Chinese Character Set (GB 18030-2000);
Code for Information Exchange (one byte)(JIS X 0201-1976).;
Code of the supplementary Japanese Graphic Character set for information interchange (JIS X 0212-1990).;
Code for the Japanese Graphic Character set for information interchange (JIS X 0208-1990),;
Code for Korean Character Set (KS X 1001);
The world wide character standard from ISO/IEC 10646-1-1993;
UCS Transformation Format, 16-bit form;
UCS Transformation Format, 32-bit form;
UCS Transformation Format, 8-bit form |
- 6210. Alpha-Beta-Omega Interferon Receptor-2
- [Encoded as 515-aa 58-kDa (precursor), 331-aa, and 515-aa isoforms by human IFNAR2 Gene (Type II Cytokine Receptor Family), ubiquitous type I membrane protein Interferon Alpha-Beta Receptor Beta Chain is the beta subunit of Interferon Alpha Receptor Complex, a heteromeric receptor for type I IFNs, alpha and beta, composed of at least 2 chains, IFNAR1 (alpha chain) and IFNAR2 (beta chain). In mediating innate immune responses to viral infection and specific interferon inhibition of virus replication, binding of alpha and beta IFNs triggers tyrosine phosphorylation of JAKs, TYK2, STAT proteins, autophosphorylation, and tyrosine phosphorylation by TYK2. IFNAR2 interacts with RACK1. (NCI) ( NCI )] (UMLS (NCI) C0254653) =Amino Acid, Peptide, or Protein; Receptor ;
| - 6260. alternate electronic
- [Payment initiated by the payor as the result of adjudicating a submitted invoice that arrived to the payor from an electronic source that did not provide a conformant set of HL7 messages (e.g. web claim submission). ( HL7V3.0 )] (UMLS (HL7) C1555704) =Intellectual Product =ActInvoiceAdjudicationPaymentGroupCode;
|
- 6211. alpha-D-glucopyranoside, methyl 6-((((2-chloroethyl)nitrosoamino)carbonyl)amino)-6-deoxy-
- [A chloroethylnitrosourea derivative that inhibits proliferation and growth of tumor cells by alkylation and cross-linkage of DNA strands of tumor cells. (NCI) ( NCI )] (UMLS (NCI) C0243666) =Organic Chemical; Pharmacologic Substance ;
| - 6261. Alternate Splicing
- [Alternate Splicing is a process in which multiple protein isoforms or products are generated from a single gene as a result of splicing together different nonconsecutive exons during the processing of initially identical nascent transcripts of a gene into mature mRNA transcripts. An exon may be connected to any one of several alternative exons to form the mRNA and generate related proteins, often in a tissue or developmental stage specific manner. ( NCI )] (UMLS (NCI) C0002345) =Genetic Function
|
- 6212. Alpha-Difluoromethylornithine
- [An antiprotozoal drug that is being studied for cancer prevention. ( NCI )] (UMLS (NCI) C0002260) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
| - 6262. ALTERNATING ESOTROPIA
- (UMLS (ICD9CM) C0152205) =Disease or Syndrome ;
|
- 6213. Alpha-Fucosyltransferases
- [Belongs to the family of EC 2.4.1 glycosyltransferases. The enzyme catalyzes the transfer o f fucose molecule from dinucleotide compound to another carbohydrate compound. ( NCI )] (UMLS (NCI) C0016790) =Amino Acid, Peptide, or Protein; Enzyme
| - 6263. ALTERNATING EXOTROPIA
- [ ] (UMLS (ICD9CM) C0152207) =Disease or Syndrome ;
|
- 6214. Alpha-methylacyl-CoA Racemase Gene
- [This gene plays a role in the formation of cholic acid in peroxisomes. ( NCI )] (UMLS (NCI) C1412374) AMACR;
AMACR Gene;
RACE;
=Gene or Genome ;
| - 6264. ALTERNATING HYPERPHORIA
- [ ] (UMLS (ICD9CM) C0152220) =Disease or Syndrome ;
|
- 6215. alpha-Phenyl-2-piperidineacetic Acid Methyl Ester
- [central stimulant used in treatment of hyperkinetic children, various types of depression, and narcolepsy. ( CSP )] (UMLS (NCI) C0025810) =Organic Chemical; Pharmacologic Substance ;
=[CN800] CNS STIMULANTS;
phenylacetate;
piperidine;
Piperidines;
[CN802] AMPHETAMINE-LIKE STIMULANTS;
=alpha-Phenyl-2-piperidineacetic Acid Methyl Ester Hydrochloride;
METHYLPHENIDATE 27 MG;
| - 6265. alternative complement pathway
- [complement activation sequence initiated by the activation of complement factor C3, which is triggered by the interaction of microbial polysaccharides and properdin without participation of an antigen-antibody reaction. ( CSP )] (UMLS (CSP) C0009546) =Molecular Function ;
=Complement Pathway;
|
- 6216. alpha-Phenyl-2-piperidineacetic Acid Methyl Ester Hydrochloride
- [The hydrochloride salt of methylphenidate, a synthetic central nervous system stimulant. Methylphenidate appears to activate the brain stem arousal system and cortex to produce its stimulant effect and, in some clinical settings, may improve cognitive function. ( NCI )] (UMLS (NCI) C0700545) =Organic Chemical; Pharmacologic Substance ;
=alpha-Phenyl-2-piperidineacetic Acid Methyl Ester;
=METHYLPHENIDATE HYDROCHLORIDE 5 MG;
METHYLPHENIDATE HYDROCHLORIDE 10 MG;
METHYLPHENIDATE HYDROCHLORIDE 20 MG;
METHYLPHENIDATE HYDROCHLORIDE 36 MG;
METHYLPHENIDATE HYDROCHLORIDE 18 MG;
METHYLPHENIDATE HYDROCHLORIDE 54 MG;
METHYLPHENIDATE HYDROCHLORIDE 40 MG;
METHYLPHENIDATE HYDROCHLORIDE 30 MG;
| - 6266. Alternative explanations for the event available
- (UMLS (HL7) C1546997) =Idea or Concept =Causality Observations;
|
- 6217. alpha-[(4-Chlorobenzoyl)amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic Acid
- [A quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulates prostaglandin EP4 receptor gene expression followed by mucous secretion, thereby enhancing the gastric mucosal defense. ( NCI )] (UMLS (NCI) C0069562) =Organic Chemical; Pharmacologic Substance ;
| - 6267. Alternative Level of Care
- [Provision of Alternate Level of Care to a patient in an acute bed. Patient is waiting for placement in a long-term care facility and is unable to return home. ( HL7V3.0 )] (UMLS (HL7) C1555460) =Intellectual Product =ActMedicalServiceCode;
|
- 6218. alpha-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile
- [calcium channel blocker that dilates coronary arteries and decreases myocardial oxygen demand. ( CSP )] (UMLS (NCI) C0042523) =Organic Chemical; Pharmacologic Substance ;
=[CV300] ANTIARRHYTHMICS;
[CV200] CALCIUM CHANNEL BLOCKERS;
Phenethylamines;
coronary vasodilator;
[CV250] ANTIANGINALS;
=(+-)-Verapamil hydrochloride;
VERAPAMIL 300 MG;
| - 6268. Alternative Macrophage Activation-Associated CC Chemokine 1
- [Induced by glucocorticoids, PMA, IL-4, IL-13, and IL-10 and expressed by human CCL18 Gene (Intercrine Beta Family) in lung, lymph nodes, placenta, bone marrow, dendritic cells, and macrophages, secreted 89-aa 10-kDa (precursor) Small Inducible Cytokine A18, an immunoregulatory chemotactic cytokine for naive T cells, CD4+ and CD8+ T cells, and nonactivated lymphocytes involved in inflammatory processes s well as humoral and cell-mediated immunity. CCL18 may be involved in B cell migration into lymph node follicles. (NCI) ( NCI )] (UMLS (NCI) C0541270) =Amino Acid, Peptide, or Protein; Immunologic Factor
|
- 6219. Alpha-[tert-butylaminomethyl]-3,4- dihydroxybenzyl alcohol 3,4-di(p-toluate) Methanesulfonate
- [The mesylate salt of bitolterol, a diester sympathomimetic amine with bronchodilator activity. As an ester prodrug, bitolterol is hydrolyzed by esterases to its active metabolite colterol (N-t-butylarterenol). Colterol selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial smooth muscle. This increases air flow and prevents bronchospasms and may eventually lead to an improvement of airway function. ( NCI )] (UMLS (NCI) C0106575) =Organic Chemical; Pharmacologic Substance =BITOLTEROL;
| - 6269. alternative medicine
- [diagnostic or therapeutic technique which is presently outside the field of conventional medical practice; for use as a 'tag' term index at 'T' emphasis level. ( CSP )] (UMLS (CSP) C0002346) =Biomedical Occupation or Discipline
|
- 6220. alpha2 macroglobulin receptor
- [ ] (UMLS (CSP) C0598787) =Amino Acid, Peptide, or Protein; Receptor
| - 6270. alternatives to animals in research
- [methods which refine, reduce, or replace the use of animals in research; includes those projects which replace one animal species with a phylogenetically lower species. ( CSP )] (UMLS (CSP) C0003059) =Research Activity ;
|
- 6221. Alphabetic
- [Alphabetic transcription of name (Japanese: romaji) ( HL7V3.0 )] (UMLS (HL7) C1553380) =Idea or Concept =NameRepresentationUse;
| - 6271. Althose
- (UMLS (NCI) C0699059) =Organic Chemical; Pharmacologic Substance
|
- 6222. Alphabetic (i.e., Default or some single-byte)
- (UMLS (HL7) C1547500) =Idea or Concept =Name/address representation;
| - 6272. altitude
- [height above sea level or above the earth's surface. ( CSP )] (UMLS (CSP) C0002349) =Quantitative Concept
|
- 6223. Alphaherpesvirinae
- [a subfamily of Herpesviridae; replicate rapidly and latent infection is often demonstrable in nerve ganglia. ( CSP )] (UMLS (CSP) C0206557) =Virus =herpes virus;
=herpes simplex virus 2;
B virus;
chickenpox virus;
herpes simplex virus 1;
suid alphaherpesvirus 1 | - 6273. altitude sickness
- [A morbid condition of ANOXIA caused by the reduced available oxygen at high altitudes. ( MSH )] (UMLS (CSP) C0002351) =Disease or Syndrome
|
- 6224. Alphanumeric
- [A term used to describe a character string containing only letters and numbers. ( NCI )] (UMLS (NCI) C0439063) =Intellectual Product
| - 6274. Altretamine/Carboplatin/Cyclophosphamide
- (UMLS (NCI) C0280871) =Therapeutic or Preventive Procedure ;
|
- 6225. AlphaPAK
- [p21-Activated Kinase 1, encoded by the PAK1 gene, shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling and serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternative transcripts of this gene have been found, but their full-length natures have not yet been determined. (from Gene) ( NCI )] (UMLS (NCI) C0299856) =Amino Acid, Peptide, or Protein; Enzyme
| - 6275. Altretamine/Carboplatin/Cyclophosphamide/Doxorubicin
- (UMLS (NCI) C0279977) =Therapeutic or Preventive Procedure
|
- 6226. alpharetrovirus
- [genus of the family retroviridae with type C morphology that causes malignant and other diseases in wild birds and domestic fowl; widespread vertically and horizontally transmitted exogenous and endogenous viruses; associated with malignancies, wasting, and osteopetrosis. ( CSP )] (UMLS (CSP) C0004423) =Virus ;
| - 6276. Altretamine/Carmustine/Mitomycin
- (UMLS (NCI) C0279189) =Therapeutic or Preventive Procedure
|
- 6227. Alphavirus
- [genus of Togaviridae, also known as Group A arboviruses, serologically related to each other but not to other Togaviridae; viruses are transmitted by mosquitoes. ( CSP )] (UMLS (CSP) C0002331) =Virus
| - 6277. Altretamine/Cisplatin
- (UMLS (NCI) C0279483) =Therapeutic or Preventive Procedure
|
- 6228. Alphax Integrin Chain
- [Part of the integrin CR4, aka Complement Receptor 4, the CD11c/CD18 heterodimer. (Fundamental Immunology, 3rd ed., William Paul, ed., Raven Press, NY 1993, pg 927) ( NCI )] (UMLS (NCI) C0023395) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
| - 6278. Altretamine/Cisplatin/Cyclophosphamide
- (UMLS (NCI) C0280604) =Therapeutic or Preventive Procedure
|
- 6229. Alport syndrome
- [hereditary disorder characterized by progressive sensorineural hearing loss, progressive pyelonephritis or glomerulonephritis, and, occasionally, ocular defects; transmitted as an autosomal dominant or X-linked trait. ( CSP )] (UMLS (CSP) C1567741) Alport's Syndrome;
=Disease or Syndrome; ;
=Hearing Loss, Sensorineural;
Genetic Condition;
nephritis;
syndrome | - 6279. Altretamine/Cisplatin/Cyclophosphamide/Doxorubicin
- (UMLS (NCI) C0056451) =Therapeutic or Preventive Procedure
|
- 6230. alprazolam
- [8-chloro-1-methyl-6-phenyl-s-triazolo benzodiazepine, has both antidepressant and anxiolytic properties; possible efficacy in alcohol withdrawal therapy; abuse can lead to habituation or addiction. ( CSP )] (UMLS (CSP) C0002333) =Organic Chemical; Pharmacologic Substance ;
| - 6280. Altretamine/Cisplatin/Cyclophosphamide/Fluorouracil
- (UMLS (NCI) C0279427) =Therapeutic or Preventive Procedure
|
- 6231. alprenolol
- [One of the ADRENERGIC BETA-ANTAGONISTS used as an antihypertensive, anti-anginal, and anti-arrhythmic agent. ( MSH )] (UMLS (CSP) C0002334) =Organic Chemical; Pharmacologic Substance ;
| - 6281. Altretamine/Cisplatin/Cyclophosphamide/Misonidazole
- (UMLS (NCI) C0279336) =Therapeutic or Preventive Procedure
|
- 6232. ALPS
- (UMLS (NCI) C1328840) ALPS (autoimmune lymphoproliferative syndrome);
Autoimmune Lymphoproliferative Syndrome;
Canale-Smith Syndrome =Disease or Syndrome ;
| - 6282. Altretamine/Cisplatin/Doxorubicin
- (UMLS (NCI) C0062074) =Therapeutic or Preventive Procedure ;
|
- 6233. ALPS2
- [Caspase-10, encoded by the CASP10 gene, is a member of the cysteine-aspartic acid protease (caspase) family. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspase-10 is involved in the activation cascade of caspases responsible for apoptosis execution. It is recruited to both FAS- and TNFR-1 receptors in a FADD dependent manner. Caspase-10 cleaves and activates Caspases-3, -4, -6, -7, -8, and -9, and itself can be processed by Caspase-8. Mutations in the CASP10 gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Four alternatively spliced transcript variants encoding different isoforms have been described for this gene. (From LocusLink, Swiss-Prot and NCI) ( NCI )] (UMLS (NCI) C0758959) Apoptotic Protease MCH-4;
CASP10;
CASP10 Protein;
Caspase 10, Apoptosis-Related;
Caspase 10, Apoptosis-Related Cysteine Protease;
Caspase-10;
Cysteine Protease;
EC 3.4.22.-;
FADD-Like ICE2;
Fas-Associated Death Domain Protein;
FAS-Associated Death Domain Protein Interleukin-1B-Converting Enzyme 2;
FLICE2;
ICE-Like Apoptotic Protease 4;
Interleukin-1B-Converting Enzyme 2;
MCH4 =Amino Acid, Peptide, or Protein; Enzyme ;
| - 6283. Altretamine/Cisplatin/Etoposide
- (UMLS (NCI) C0281013) =Therapeutic or Preventive Procedure
|
- 6234. ALRT1057
- (UMLS (NCI) C0918022) =Organic Chemical; Pharmacologic Substance ;
| - 6284. Altretamine/Cisplatin/Etoposide/Mitomycin
- (UMLS (NCI) C0065958) =Therapeutic or Preventive Procedure
|
- 6235. ALS
- [progressive degeneration of the neurons that give rise to the corticospinal tract and of the motor cells of the brain stem and spinal cord, resulting in a deficit of upper and lower motor neurons. ( CSP )] (UMLS (CSP) C0002736) =Disease or Syndrome
| - 6285. Altretamine/Cyclophosphamide/Doxorubicin
- (UMLS (NCI) C0279470) =Therapeutic or Preventive Procedure
|
- 6236. AlS2Pc
- [An amphiphilic compound that exhibits a direct phototoxic effect, thereby inducing tumor necrosis. (NCI) ( NCI )] (UMLS (NCI) C0081549) =Organic Chemical; Pharmacologic Substance
| - 6286. Altretamine/Cyclophosphamide/Doxorubicin/Fluorouracil/Fluoxymesterone/Methotrexate/Prednisone/Tamoxifen/Vinblastine
- (UMLS (NCI) C0280615) =Therapeutic or Preventive Procedure
|
- 6237. Alsatian
- [The German Shepherd Dog is also known as the Alsatian. It is well proportioned and very strong. The coat most often comes in black with tan, sable or all black. It has a sturdy, muscular, slightly elongated body with a light but solid bone structure. It has round feet with very hard soles. Height: 22-26 inches (55-65 cm.) Weight: 77-85 pounds (35-40 kg.) ( NCI )] (UMLS (NCI) C0324373) =Mammal
| - 6287. Altretamine/Cyclophosphamide/Doxorubicin/Prednisone/Vincristine
- (UMLS (NCI) C0279335) =Therapeutic or Preventive Procedure
|
- 6238. AlSPc
- [A rhodamine-based dye used as a photosensitizing agent in cytotoxic photodynamic therapy. (NCI) ( NCI )] (UMLS (NCI) C0055390) =Organic Chemical; Pharmacologic Substance ;
| - 6288. Altretamine/Cyclophosphamide/Doxorubicin/Vincristine
- (UMLS (NCI) C0279183) =Therapeutic or Preventive Procedure
|
- 6239. alstonia
- [A plant genus of the family APOCYNACEAE. Members contain echitovenidine, echitamine, venenatine (an indole alkaloid), and anti-inflammatory triterpenoids ( MSH )] (UMLS (CSP) C0599279) =Plant
| - 6289. Altretamine/Cyclophosphamide/Fluorouracil/Methotrexate
- (UMLS (NCI) C0062594) =Therapeutic or Preventive Procedure
|
- 6240. Alstrom syndrome
- [ ] (UMLS (CSP) C0268425) =Congenital Abnormality; Disease or Syndrome
| - 6290. Altretamine/Cyclophosphamide/Methotrexate
- (UMLS (NCI) C0279409) =Therapeutic or Preventive Procedure
|
- 6241. ALT
- [Activity measured as a test of liver function, human Glutamic-Pyruvate Transaminases (Alanine Aminotransferase Family) are pyridoxal phosphate-dependent enzymes involved in cellular nitrogen metabolism, amino acid metabolism, and liver gluconeogenesis. Glutamic Pyruvic Transaminases mediate conversion of major intermediate metabolites, catalyzing reversible transamination between alanine and alpha-ketoglutarate to form pyruvate and glutamate. (NCI) ( NCI )] (UMLS (NCI) C0376147) =Amino Acid, Peptide, or Protein; Enzyme
| - 6291. Altretamine/Doxorubicin/Fluorouracil/Mitomycin
- (UMLS (NCI) C0279486) =Therapeutic or Preventive Procedure
|
- 6242. ALT ESOTROP W X/Y PATTRN
- [ ] (UMLS (ICD9CM) C0155327) =Disease or Syndrome
| - 6292. Altretamine/Doxorubicin/Fluoxymesterone/Methotrexate/Mitolactol/Prednisone/Tamoxifen/Vincristine
- (UMLS (NCI) C0280614) =Therapeutic or Preventive Procedure
|
- 6243. ALT ESOTROPIA W A PATTRN
- [ ] (UMLS (ICD9CM) C0155325) =Disease or Syndrome
| - 6293. Altretamine/Doxorubicin/Melphalan
- (UMLS (NCI) C0279477) =Therapeutic or Preventive Procedure
|
- 6244. ALT ESOTROPIA W V PATTRN
- [ ] (UMLS (ICD9CM) C0155326) =Disease or Syndrome
| - 6294. Altretamine/Doxorubicin/Methotrexate
- (UMLS (NCI) C0279479) =Therapeutic or Preventive Procedure
|
- 6245. ALT EXOTROP W X/Y PATTRN
- [ ] (UMLS (ICD9CM) C0155333) =Disease or Syndrome
| - 6295. Altretamine/Etoposide
- (UMLS (NCI) C0281629) =Therapeutic or Preventive Procedure
|
- 6246. ALT EXOTROPIA W A PATTRN
- [ ] (UMLS (ICD9CM) C0155331) =Disease or Syndrome
| - 6296. Altretamine/Etoposide/Methotrexate
- (UMLS (NCI) C0280599) =Therapeutic or Preventive Procedure
|
- 6247. ALT EXOTROPIA W V PATTRN
- [ ] (UMLS (ICD9CM) C0155332) =Disease or Syndrome
| - 6297. Altretamine/Etoposide/Procarbazine
- (UMLS (NCI) C0279464) =Therapeutic or Preventive Procedure
|
- 6248. Altace
- (UMLS (NCI) C0878061) =Organic Chemical; Pharmacologic Substance
| - 6298. Altretamine/Lomustine/Methotrexate
- (UMLS (NCI) C0279430) =Therapeutic or Preventive Procedure
|
- 6249. Alteration In Cognition
- [Pertaining to or characterized by cognition. That operation of the mind which we become aware of objects of thought or perception; it includes all aspects of perceiving, thinking, or remembering. ( NCI )] (UMLS (NCI) C1392786) Alteration Of Cognitive Function;
Changes, cognitive;
Cognitive Alteration;
Cognitive Change;
Cognitive Changes =Mental or Behavioral Dysfunction ;
| - 6299. Altretamine/Mitomycin/Vinblastine
- (UMLS (NCI) C0291012) =Therapeutic or Preventive Procedure
|
- 6250. Alteration in Respiration
- (UMLS (NCI) C0184551) =Finding ;
| - 6300. Altretamine/Paclitaxel
- (UMLS (NCI) C0281302) =Therapeutic or Preventive Procedure ;
|
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