UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
AF AF AF- AF0 AF1 AF4 AF6 AF9 AFA AFB AFD AFF AFG AFI AFL AFM AFO AFP AFQ AFR AFT AFX
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1. AF-1
[Encoded by human IFNGR2 Gene (Type II Cytokine Receptor Family), 337-aa 38-kDa (precursor) type I membrane protein Interferon Gamma Receptor Beta Chain is an integral accessory factor subunit of Interferon Gamma Receptor Complex required for signal transduction. Ser/Thr phosphorylated IFN Gamma Receptor activates macrophages in innate immune responses to viral infection and host defenses. Ligand-bound receptor activates JAK kinases leading to tyrosine phosphorylation of STAT1 and STAT2. IFNGR1 constitutes the receptor ligand-binding alpha chain. Containing 2 fibronectin type III domains, IFNGR2 may interact with GAF, JAK1, and/or JAK2. (NCI) ( NCI )] (UMLS (NCI) C1334196) IFGR2;
Interferon Gamma Receptor Accessory Factor-1;
Interferon Gamma Receptor Beta Chain;
Interferon Gamma Receptor-2;
Interferon Gamma Transducer-1;
=Amino Acid, Peptide, or Protein; Receptor ;

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