PDGFRL

1. [This gene may play a role in the negative regulation of cell growth. ( NCI )]
   UMLS (NCI) C1335203
   
   PDGFRL Gene
   Platelet-Derived Growth Factor Receptor-Like Gene
    

   Gene or Genome

2. [Platelet-Derived Growth Factor Receptor-Like Protein, encoded by the PDGFRL gene, has significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. (from LocusLink) ( NCI )]
   UMLS (NCI) C1335431
   
   Platelet-Derived Growth Factor Receptor-Like
   Platelet-Derived Growth Factor Receptor-Like Protein
   Platelet-Derived Growth Factor-Beta-Like Tumor Suppressor
    

   Amino Acid, Peptide, or Protein

   Biologically Active Substance