[Maspin is a member of the Serpin protein family. Unlike other members of the family, Maspin exhibits no protease inhibitory activity (see J Biol Chem. 2002 Dec 6;277(49):46845-8. Epub 2002 Oct 15), but it plays a role in cell-matrix adhesion, tumor invasion, and metastasis. High maspin expression appears to oppose lymph node metastasis. Higher expression is associated with better survival rates and may be a favorable prognostic marker. (from SWISS-PROT, OMIM, and NCI) ( NCI )]
UMLS (NCI) C0250870 - Amino Acid, Peptide, or Protein
- Pharmacologic Substance
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