- 1. M-Azidopyrimethamine
- [An antifolate derived from diaminopyrimidine with cytotoxic properties. With a mechanism of action similar to that of methotrexate (MTX), m-azidopyrimethamine blocks tetrahydrofolate synthesis, resulting in depletion of nucleotide precursors and inhibition of DNA, RNA and protein synthesis. This agent is more lipophilic but less potent than MTX. (NCI04) ( NCI )] (UMLS (NCI) C0280485) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 2. MAZINDOL
- [5-(p-chlorophenyl)-2,5-dihydro-3H- imidazo(2,1-a)isoindol-5-ol; mimics cocaine and amphetamines by inhibiting catecholamine uptake in CNS synapses, but is not reinforcing or abused; used as a molecular probe and to reduce cocaine craving. ( CSP )] (UMLS (NCI) C0024977) =Organic Chemical; Pharmacologic Substance ;
=[GA750] APPETITE SUPPRESSANTS; benzimidazole; Indole; [CN802] AMPHETAMINE-LIKE STIMULANTS =MAZINDOL 2 MG; MAZINDOL 1 MG; |