[A Leydig cell tumor characterized by large tumor size, and the presence of cytologic atypia, increased mitotic activity, necrosis, and vascular invasion. Approximately 10% of the testicular Leydig cell tumors show malignant characteristics and metastasize. Leydig cell tumors of the ovary follow a benign clinical course. ( NCI )]
UMLS (NCI) C0334410