[Encoded by MAGED1 Gene (MAGE Family), ubiquitous 778-amino acid 86-kD cytoplasmic NRAGE Protein contains a 200-amino acid MAGE homology domain. NRAGE appears to shift from cytoplasm to plasma membrane upon NGF stimulation to interact with p75NTR. NRAGE antagonizes p75NTR association with TRKA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. NRAGE may regulate the function of DLX family members. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )]
UMLS (NCI) C0960824MAGE-D1 Antigen
Melanoma-Associated Antigen D1
NRAGE Protein
PRO2292
Urotrophin Receptor-Interacting MAGE Homolog Protein
- Amino Acid, Peptide, or Protein
- Biologically Active Substance