[The tromethamide salt form of lodoxamide, a synthetic mast cell stabilizing compound with ant-inflammatory activity. Upon administration to the eye, lodoxamide tromethamide inhibits type I immediate hypersensitivity reaction by preventing the antigen-stimulated calcium influx into mast cells, thereby inhibiting release of histamine. Lodoxamide tromethamide also prevents the release of slow-reacting substances of anaphylaxis (SRS-A) and inhibits eosinophil chemotaxis. ( NCI )]
UMLS (NCI) C0065148 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: Oxamic Acid
1,3-Propanediol, 2-Amino-2-(hydroxymethyl)-
LODOXAMIDE
Relation/CHD: LODOXAMIDE TROMETHAMINE 0.1 %