- 1. L-3-(3,4-Dihydroxyphenyl)-2-methylalanine Ethyl Ester Hydrochloride
- [The hydrochloride salt form of methyldopa, a phenylalanine derivate and aromatic amino acid decarboxylase inhibitor with antihypertensive activity. Methyldopa is a prodrug and is metabolized in the central nervous system. The antihypertensive action of methyldopa seems to be attributable to its conversion into alpha-methylnorepinephrine, which is a potent alpha-2 adrenergic agonist that binds to and stimulates potent central inhibitory alpha-2 adrenergic receptors. This results in a decrease in sympathetic outflow and decreased blood pressure. ( NCI )] (UMLS (NCI) C0304527) =Organic Chemical; Pharmacologic Substance =METHYLDOPATE;
=METHYLDOPATE HYDROCHLORIDE 50 MG/ML | - 6. LDL Precipitation
- (UMLS (HL7) C1550106) =Therapeutic or Preventive Procedure =Therapeutic Interventions;
◊ (UMLS (HL7) C1551378) Laboratory Procedure ActSpecimenTreatmentCode; |
- 2. l-Deprenyl
- [A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl. ( MSH )] (UMLS (NCI) C0036579) =Organic Chemical; Pharmacologic Substance ;
=[CN500] ANTIPARKINSON AGENTS;
Phenethylamines =(-)-Phenylisopropylmethylpropynylamine;
| - 7. LDL receptor
- [family of receptors; members include low density lipoprotein receptor, alpha 2-macroglobulin receptor, low density lipoprotein receptor related protein, and kidney proximal tubule membrane protein. ( CSP )] (UMLS (CSP) C0034821) =Amino Acid, Peptide, or Protein; Receptor ;
=Cell Surface Receptor;
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- 3. LD-50
- [The median lethal dose. the dose of a chemical or biologic preparation (e.g., a bacterial exotoxin or a suspension of bacteria) that is likely to cause death in 50% of the animals being tested; it varies in relation to the type of animal and the route of administration; (the absolute lethal dose is LD100, and minimal lethal dose is LD05). ( NCI )] (UMLS (NCI) C0023378) =Quantitative Concept
| - 8. LDLR
- [This gene plays a role in the modulation of ligand-specific receptor-mediated endocytosis, and also plays a regulatory role in cholesterol synthesis. ( NCI )] (UMLS (NCI) C1366529) LDLR Gene;
Low Density Lipoprotein Receptor (Familial Hypercholesterolemia) Gene =Gene or Genome |
- 4. LDL
- [class of lipoproteins responsible for transport of cholesterol to extrahepatic tissues; they are formed in the circulation when very-low-density lipoproteins are degraded first to intermediate-density lipoproteins and then to LDL by the gain and loss of specific apolipoproteins and the loss of most of their triglycerides; LDL are taken up and catabolized by both the liver and extrahepatic tissues by specific receptor-mediated endocytosis. ( CSP )] (UMLS (NCI) C0023823) =Amino Acid, Peptide, or Protein; Lipid; Biologically Active Substance =blood lipoprotein;
| - 9. LDP 341
- (UMLS (NCI) C1135131) =Organic Chemical; Pharmacologic Substance ;
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- 5. LDL
- [A quantitative measurement of the amount of LDL cholesterol present in a sample of serum. ( NCI )] (UMLS (NCI) C0428474) =Laboratory Procedure
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