[genetic phenomenon due to deletion or mutation in one allele of a polymorphic gene, as detected by expression after cell fusion; used as a test for tumor-promoting mutations; do not confuse with "loss of heterogeneity" which applies to diverse cell populations within a tissue. ( CSP )]
UMLS (NCI) C0524869 - Genetic Function
- Cell or Molecular Dysfunction
Relation/PAR: Chromosomal Deletion
DNA Alteration
neoplasm/cancer diagnosis