[Copine VII, encoded by the human CPNE7 gene, is a calcium-dependent membrane-binding protein. Molecular events at the interface of the cell membrane and cytoplasm may be regulated by proteins that attach to and detach from the membrane surface in response to signals. Calcium-dependent membrane-binding proteins may play such a role. Copine VII contains two N-terminal C2 domains and one von Willebrand factor A domain. It may function in membrane trafficking. Two isoforms (1 and 2) may be produced by alternative splicing. This gene has been excluded as a candidate in sporadic breast cancers with loss of heterozygosity at 16q24.3. (NCI) ( NCI )]
UMLS (NCI) C0910379Copine VII
CPNE7
CPNE7 Protein
MGC34192
- Amino Acid, Peptide, or Protein
- Biologically Active Substance