Citrate of Magnesia

[The citrate salt of the element magnesium with laxative properties. The cathartic action of magnesium cations appears to result, in part, from osmotically mediated water retention, which subsequently stimulates peristalsis. In addition, magnesium ions may also stimulate the activity of nitric oxide (NO) synthase and increase the biosynthesis of the phospholipid proinflammatory mediator platelet activating factor (PAF) in the gut. NO may stimulate intestinal secretion via prostglandin- and cyclic GMP-dependent mechansisms while PAFproduces significant stimulation of colonic secretion and gastrointestinal motility. ( NCI )]

UMLS (NCI) C0126774

Organic Chemical
Pharmacologic Substance

Relation/PAR: [TN406] MAGNESIUM
Organometallic Compound
2-Hydroxy-1,2,3-propanetricarboxylic Acid
[GA202] HYPEROSMOTIC LAXATIVES
CITRATE

Relation/CHD: MAGNESIUM CITRATE LIQUID,ORAL
BISACODYL 10MG SUPP/BISACODYL 5MG TAB #3/MG CIT 300ML
MAGNESIUM CITRATE 1.2 OZ
MAGNESIUM CITRATE 300 ML
MAGNESIUM CITRATE SOLUTION

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