[Embryonal Carcinoma is composed of large cells that proliferate in cohesive nests and sheets, form abortive papillae, or line irregular, gland-like spaces. In rare occasions, tumor cells may replicate the structure of the early embryo, forming "embryoid bodies" replete with germ discs and miniature amniotic cavities. The tumors also have enlarged nucleoli, abundant clear to somewhat violet-hued cytoplasm, a high mitotic rate and zones of coagulative necrosis. (Adapted from WHO.) ( NCI )]
UMLS (NCI) C1333377Embryonal Carcinoma of CNS
Embryonal Carcinoma of the Central Nervous System