[Encoded by human HOXA10 Gene (ABD-B Family) and expressed spatially/temporally in posterior domains during genitourinary development, 496- and 494-amino acid 41-kD Homeobox Protein A10 isoforms are inhibitory transcription factors, containing a common DNA-binding homeobox domain, that may regulate morphogenesis and differentiation by providing anterior-posterior positional identity. HOXA10 protein is also expressed in adult endometrium during early pregnancy. Bound to 5-prime AA[AT]TTTTATTAC 3-prime DNA, HOXA10 may mediate progesterone regulation of uterine EP3 and EP4. HOXA10 also appears to regulate hematopoietic lineage commitment. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )]
UMLS (NCI) C1334038Homeobox Protein 1H
Homeobox Protein A10
Homeobox Protein HOXA10
HOX1.8
HOX1H
HOXA10
HOXA10 Protein
- Amino Acid, Peptide, or Protein
- Biologically Active Substance