Cefuroxime Axetil

[A second generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefuroxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefuroxime inhibits bacterial septum and cell wall synthesis formation. ( NCI )]

UMLS (NCI) C0055015

Organic Chemical
Antibiotic

Relation/PAR: CEFUROXIME

Relation/CHD: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)acetyl)amino)-8-oxo-, Monosodium Salt(6R-(6alpha,7beta(Z)))-
CEFUROXIME AXETIL 125 MG/5ML
CEFUROXIME AXETIL 125 MG
CEFUROXIME AXETIL 250 MG
CEFUROXIME AXETIL 500 MG
CEFUROXIME AXETIL 250 MG/5ML

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