[Encoded by human CST6 Gene, 149-amino acid 16.5 kD (precursor) Cystatin 6 is a type 2 cystatin. Cystatin superfamily proteins contain multiple cystatin-like sequences. Three inhibitory subfamilies display structural and functional similarities: type 1 stefins, type 2 cystatins, and kininogens. Some members are cysteine protease inhibitors, while others have lost or never acquired inhibitory activity. Type 2 cystatins are endogenous intracellular or extracellular cysteine proteinase inhibitors that appear to provide protective functions. (from Swiss-Prot, OMIM, and NCI) ( NCI )]
UMLS (NCI) C0534343 - Amino Acid, Peptide, or Protein
- Pharmacologic Substance