[Ubiquitously expressed by human CDC91L1 Gene (PIGU Family), conserved 435-aa 50-kD GPI Transamidase Component PIGU is an integral ER membrane protein containing 9 putative transmembrane domains, with similarity to Cdc91 (S. cerevisiae), and a critical subunit of the GPI transamidase complex (PIGU, PIGK/GPI8, PIGS, PIGT, and GPAA1/GAA1) that attaches posttranslational GPI-anchors to the C-termini of cell surface proteins attached to membranes via GPI. PIGU may be involved in recognition of the GPI attachment signal or the lipid portion of GPI. (NCI) ( NCI )]
UMLS (NCI) C1453971CDC91-Like 1 Protein
Cell Division Cycle 91-Like 1 Protein
Cell Division Cycle Protein 91-Like 1 Protein
GPI Transamidase Component
GPI Transamidase Component PIGU
Phosphatidylinositol-Glycan Biosynthesis Class U Protein
PIGU
UNQ3055/PRO9875
- Amino Acid, Peptide, or Protein
- Biologically Active Substance