CAP43

[Expressed most prominently in placenta, prostate, kidney, small intestine, and ovary, human NDRG1 Gene (NDRG Family, Alpha/Beta Hydrolase Superfamily) encodes ubiquitous cytoplasmic N-Myc Downstream Regulated Protein 1, also associated with the plasma membrane and nucleus. Downregulated by NMYC and rapidly induced by okadaic acid, a serine/threonine phosphatase inhibitor, increased NDRG1 levels are induced by an elevation of free intracellular calcium ion; cells that border lumenae show highest expression. Involved in stress responses, hormone responses, cell growth, and differentiation, NDRG1 may have a growth inhibitory role. (NCI) ( NCI )]

UMLS (NCI) C0916139

Differentiation-Related Gene 1 Protein
DRG1
NDR1
NDRG1
NDRG1 Protein
Nickel-Specific Induction Protein CAP43
N-Myc Downstream Regulated Protein 1
Protein Regulated By Oxygen-1
Reducing Agents and Tunicamycin-Responsive Protein
RIT42
RTP
Tunicamycin-Responsive Protein

Amino Acid, Peptide, or Protein
Biologically Active Substance

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