[Identified as a novel Fms-interacting protein. Overexpression in a bipotential myeloid progenitor cell line prevented M-CSF induced macrophage differentiation. Instead, cells differentiated into granulocytes. Thus, appears to have an effect on lineage commitment. (from Oncogene 1999;18:6488-95) ( NCI )]
UMLS (NCI) C1334876Chromosome 22 Open Reading Frame 19
- Amino Acid, Peptide, or Protein
- Biologically Active Substance