[Encoded by human HPCA Gene (Recoverin Subfamily), 192-amino acid 22-kD neuron-specific Hippocalcin is myristoylated, plasma membrane-associated, binds two Ca(2+) ions, and contains the EF-hand Ca(2+)-binding motif. Human amino acid sequence shows complete identity (and 92% nucleotide identity) with rat; it is also identical to mouse hippocalcin. Hippocalcin shows striking similarity to photoreceptor Ca(2+)-sensitive proteins that regulate photosignal transduction. Displaying recoverin activity and a Ca(2+)-dependent inhibition of rhodopsin kinase, it may be involved in the Ca(2+)-dependent regulation of rhodopsin phosphorylation. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )]
UMLS (NCI) C1505568Hippocalcin
HPCA
HPCA Protein
Neuron Specific Calcium Binding Protein Hippocalcin
p23K
- Amino Acid, Peptide, or Protein
- Biologically Active Substance